ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2020, Vol. 12 ›› Issue (1): 17-20.doi: 10.3969/j.issn.1674-3865.2020.01.005

• 中药儿科疾病应用专栏 • 上一篇    下一篇

补中益气汤在小儿急性上呼吸道感染中退热作用的研究

李娇，罗光亮，黄文娴，何薇，张俊绮   

  1. 518034 广东 深圳，广州中医药大学深圳医院（福田）中医儿科
  • 出版日期:2020-02-25 发布日期:2021-05-17
  • 通讯作者: 罗光亮，E-mail：luogl65@163.com
  • 作者简介:李娇（1987-），女，医学硕士，主治医师。研究方向：小儿多动症、呼吸及消化道相关疾病中西医结合防治

Study on antipyretic effect of Buzhong Yiqi decoction in children with acute upper respiratory tract infection

  • Online:2020-02-25 Published:2021-05-17

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摘要： 目的 分析补中益气汤在小儿上呼吸道感染并发热治疗中有关增强退热效果、缩短完全退热时间及减少反复发热次数等作用的研究。 方法 选择2018年3月至2019年6月广州中医药大学深圳医院儿科门诊治疗的急性上呼吸道感染合并发热患儿83例，根据患儿有无口服中药，分为中药组43例和常规组40例。常规组患儿在基础治疗同时，给予布洛芬混悬液退热治疗。中药组患儿在常规组基础上采用补中益气汤辅助退热治疗。比较两组患儿的临床疗效、退热时间和反复发热次数等。 结果 两组临床总有效率及治疗3 d内显愈率比较差异无统计学意义（P>0.05）。中药组前3天内服药后体温恢复正常范围且3 d内均无反复发热的患儿人数明显高于常规组，差异有统计学意义（P<0.05）。两组患儿平均退热时间比较差异无统计学意义（P>0.05）。两组患儿服药后退热起效时间比较差异无统计学意义（P>0.05）；中药组反复发热次数和完全退热时间明显小于常规组，差异有统计学意义（P<0.05）。 结论 小儿上呼吸道感染合并发热的临床治疗中，在常规治疗基础上用补中益气汤辅助退热治疗，能够增强临床治疗效果，缩短患儿完全退热时间，减少反复发热次数，促进患儿康复。

关键词: 急性上呼吸道感染, 发热, 补中益气汤, 儿童

Abstract: Objective To analyze the effects of Buzhong Yiqi decoction in the treatment of children with acute upper respiratory tract infection and fever,such as enhancing the antipyretic effect,shortening the time of complete fever abatement and reducing the number of repeated fever Methods A retrospective analysis was carried out in 83 children with acute upper respiratory tract infection complicated with fever treated at pediatric outpatient department of Shenzhen Hospital of Guangzhou University of Traditional Chinese Medicine from March 2018 to June 2019 Based on whether they take the decoction,the children were divided into two groups:43 in the TCM group and 40 in the conventional group The children in the conventional group were given ibuprofen suspension to relieve fever in addition to the antiinflammation and rehydration treatment The children in Traditional Chinese Medicine(TCM) group were treated with Buzhong Yiqi decoction besides the treatment for conventional group to bring down the fever The clinical efficacy,antipyretic time and number of repeated fever were compared between the two groups Results There was no significant difference in the total effective rate or the 3d cure rate between the two groups（P>0.05） The number of children in the TCM group whose temperature recovered to normal within 3 days without recurrence of fever within 3 days was significantly higher than those in the conventional group(P<0.05) There was no significant difference in the mean time of fever abatement or the mean time of fever abatement or the onset time of fever abatement between TCM group and the conventional group（P>0.05）,but the number of fever recurrence and the time of complete fever abatement in TCM group were significantly less than those in the conventional group,and the difference was statistically significant (P<0.05) Conclusion In the clinical treatment for children with acute upper respiratory tract infection complicated with fever,the use of Buzhong Yiqi decoction as an adjunctive antipyretic therapy on the basis of routine treatment can enhance the clinical therapeutic effect,shorten the complete antipyretic time,reduce the number of repeated fever,and promote the rehabilitation of children

Key words: Acute upper respiratory tract infection, Fever, Buzhong Yiqi decoction, Children