ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2020, Vol. 12 ›› Issue (2): 124-127.doi: 10.3969/j.issn.1674-3865.2020.02.008

• 综述 • 上一篇    下一篇

儿童肺炎支原体感染致中枢神经系统损害研究进展

高科,赵武,杭航,刘义,宋慧芳   

  1. 233004 安徽 蚌埠,蚌埠医学院第一附属医院儿科
  • 出版日期:2020-04-25 发布日期:2021-05-17
  • 通讯作者: :赵武,E-mail:jellifish@163.com
  • 作者简介:高科(1993-),男,医师。研究方向:儿科呼吸系统疾病的诊治

Research progress in central nervous system damage caused by Mycoplasma pneumoniae infection in children

  • Online:2020-04-25 Published:2021-05-17

摘要: 肺炎支原体为儿童期呼吸道常见的病原体之一,不仅可以引起呼吸道表现,还能引起肺外表现,影响神经系统的疾病包括周围神经系统和中枢神经系统,是最严重的。在某些情况下,尤其是涉及中枢神经系统的情况下,肺炎支原体相关的神经系统疾病可导致死亡或持续性神经问题。应用血清学的检查方法诊断肺炎支原体感染中枢神经系统特异性和敏感性均不高,在脑脊液中也很难检测到肺炎支原体。由于肺炎支原体感染中枢神经系统的发病机制仍不明确,因此在临床上其治疗方案仍存在较大争议。

关键词: 肺炎支原体, 中枢神经系统, 发病机制, 治疗, 儿童

Abstract: Mycoplasma pneumoniae is one of common respiratory pathogens in children.It not only can cause respiratory manifestations,but also can cause extrapulmonary manifestations.The diseases affecting the nervous system,both the peripheral (PNS) and the central nervous system (CNS),are the most severe.In some cases,particularly when the CNS is involved,M.pneumoniae-related neuropathies can lead to death or persistent neurologic problems.The diagnostic specificity and sensitivity of Mycoplasma pneumoniae infection in the central nervous system is not high by serologic examination,and it was difficult to detect MP in CSF.As the pathogenesis of MP infection in central nervous system is still unclear,its treatment is still controversial in clinical practice

Key words: Mycoplasma pneumoniae, Central nervous system, Pathogenesis, Treatment, Children