ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2020, Vol. 12 ›› Issue (4): 291-294.doi: 10.3969/j.issn.1674-3865.2020.04.005

• 综述 • 上一篇    下一篇

儿童感染后闭塞性细支气管炎的研究进展

任丽芳,赵慧敏,鲁珊珊,肖夏夏,孙中厚   

  1. 261000 山东 潍坊,潍坊医学院儿科学专业研究生(任丽芳,赵慧敏,鲁珊珊);潍坊市人民医院儿科(肖夏夏,孙中厚)
  • 出版日期:2020-08-25 发布日期:2021-05-17
  • 通讯作者: 孙中厚,E-mail:szh65@sina.com
  • 作者简介:任丽芳(1992-),女,潍坊医学院2018级硕士研究生在读。研究方向:小儿呼吸及重症疾病的诊治

Research progress in postinfection-bronchiolitis obliterans in children

  • Online:2020-08-25 Published:2021-05-17

摘要: 儿童感染后闭塞性细支气管是儿童最为常见的闭塞性细支气管炎。病理特点是肺部小气道狭窄及阻塞,进而肺部纤维化。临床表现以持续性咳喘,呼吸急促、呼吸困难为主,预后差。结合相关辅助检查协诊。治疗上糖皮质激素类药物可作为靶向治疗药物,也支持大环内酯类抗生素、白三烯受体拮抗剂及氧疗等对症治疗。由于预后较差,极少数患儿可行移植治疗。

关键词: 闭塞性细支气管, 感染后, 诊断, 治疗, 儿童

Abstract: Postinfection-bronchiolitis obliterans in children is the most common bronchiolitis obliterans in children. The pathological features are small airway stenosis and occlusion in lung, and pulmonary fibrosis. Clinical manifestations mainly include persistent cough and asthma, polypnea and dyspnea,with poor prognosis. The diagnosis also depends on the related auxiliary examinations. In the treatment, glucocorticoid drugs can be used as the targeted therapy drugs, and the macrolides, leukotriene receptor antagonist and oxygen therapy are also useful. Because of the poor prognosis, transplantation is feasible in very few children.

Key words: Bronchiolitis obliteran, Postinfection, Diagnosis, Treatment, Children