ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (1): 52-.

• 临床研究 • 上一篇    下一篇

106例小儿药物中毒发生情况及危险因素分析

刘冬   

  1. 455000 河南 安阳,安阳市妇幼保健院儿科急诊
  • 出版日期:2021-02-25 发布日期:2021-05-17
  • 通讯作者: 刘冬,E-mail:kuangdi44764@163.com
  • 作者简介:刘冬(1984-),男,主治医师。研究方向:儿科急诊、重症医学

Analysis of the occurrence and risk factors of drug poisoning in 106 children

LIU Dong   

  1. Emergency Department of Pediatrics, Anyang Maternal and Child Health Hospital,Anyang 455000,China
  • Online:2021-02-25 Published:2021-05-17

摘要: 目的:探讨引起小儿药物中毒发生情况并分析其诱因。
方法:以2016年9月至2019年9月本院收治的106例药物中毒小儿为研究对象,采用横断面研究模式,分析中毒患儿中常见药物及临床表现,同期以160例非药物中毒患儿为对照组,两组均发放问卷调查,分析影响患儿中毒的危险因素。
结果:(1)106例患儿中34.91%为3~6岁,57.55%居住地为农村,25.47%使用抗生素,37.74%中毒途径为消化道,64.15%中毒原因为成人给药较多。(2)中毒患儿的临床表现中,77.36%患儿出现心率过快;65.09%患儿出现呼吸系统异常症状;63.21%患儿出现神经系统症状;48.11%患儿皮肤潮红;41.51%患儿出现消化系统症状;30.19%患儿表现为尿液异常;无亲属陪伴、无家庭药品专门管理、家长未严格给药均是导致小儿药物中毒的独立危险因素,而良好的教育背景、保持呼吸通畅入院急救等因素均是保护因素,差异均有统计学意义(P<0.05)。
结论:小儿药物中毒常累及多个系统,无家属陪伴、家长文化程度低及未进行药物管理、急救常识缺乏等均是导致药物中毒的危险因素。

关键词: 药物中毒, 诱因, 危险因素, 儿童

Abstract: Objective:To investigate the occurrence of drug poisoning in children and analyze the causes.
Methods:Totally 106 cases of drugpoisoned children admitted to our hospital from September 2016 to September 2019 were included as the research subjects. A cross-sectional study model was used to analyze common drugs and clinical manifestations in children with poisoning. During the same period, 160 cases of non-drug-poisoned children were taken as the control group. Both groups were given questionnaires to analyze the risk factors that affected children with poisoning.
Results:(1) Among 106 children, 34.91% were 3-6 years old, 57.55% lived in rural areas, 25.47% used antibiotics, 37.74% were poisoned through the digestive tract, and 64.15% were poisoned by adults. (2) Among the clinical manifestations of children with poisoning, 77.36% of children had a rapid heart rate; 65.09% of children had abnormal respiratory symptoms; 63.21% of children had neurological symptoms; 48.11% of children had skin flushing; 41.51% of children had symptoms of the digestive system; 30.19% of children had abnormal urine; lack of company of relatives, lack of family medicine management, and parents not strictly administering drugs were the independent risk factors for drug poisoning in children, and a good education background and keeping breathing smoothly on visiting hospital for emergency treatment were all protective factors, and the differences were statistically significant(P<0.05).
Conclusion:Drug poisoning in children often involves multiple systems. Being unaccompanied by family members, parents' low education level, lack of drug management, and lack of first aid knowledge are all risk factors for drug poisoning

Key words: Drug poisoning, Incentives, Risk factors, Children