ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2023, Vol. 15 ›› Issue (6): 467-473.doi: 10.3969/j.issn.1674-3865.2023.06.002

• 儿童抽动障碍康复专栏 • 上一篇    下一篇

基于数据分析对马融教授辨治儿童抽动障碍的经验研究

刘璇, 张喜莲, 戎萍, 马融   

  1. 300381天津,天津中医药大学第一附属医院,国家中医针灸临床医学研究中心

  • 收稿日期:2023-09-06 出版日期:2023-12-25 上线日期:2023-12-25
  • 通讯作者: 马融,E-mail:mr1974@163.com
  • 基金资助:
    中医药传承与创新“百千万”人才工程(岐黄工程)岐黄学者(国中医药人教发〔2018〕12号);天津中医药大学第一附属医院“拓新工程”基金科研课题(201932)

An empirical study on Professor Ma Rong′s treatment for children′s tic disorder based on data analysis

LIU Xuan, ZHANG Xilian, RONG Ping, MA Rong   

  1. Pediatric Department,First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine,National Clinical Medical Research Center of TCM Acupuncture and Moxibustion,Tianjin 300381,China

  • Received:2023-09-06 Published:2023-12-25 Online:2023-12-25
  • Contact: MA Rong,E-mail:mr1974@163.com

摘要: 目的 总结马融教授辨治儿童抽动障碍的临床经验。方法 建立中医药治疗抽动障碍有效病例数据库,运用频数分布、聚类分析及关联规则进行数据分析。结果 马融教授辨治儿童抽动障碍前5位的中医证型是肝亢风动证、外风引动证、脾虚痰聚证、脾虚肝亢证、气郁化火,筛选出各个证型的药物频次、药物组合主次,演化得到核心组方。结论 肝亢风动证的核心组方是天麻、钩藤、石决明、全蝎、菊花、龙骨、牡蛎;外风引动证的核心组方是连翘、甘草、薄荷、金银花、荆芥穗、黄芩、芦根、枳壳、桔梗、牛蒡子、全蝎;脾虚痰聚证的核心组方是石菖蒲、胆南星、枳壳、半夏、茯苓、陈皮、甘草、川芎、天麻、全蝎、磁石、青礞石、铁落花、羌活、党参;脾虚肝亢证的核心组方是柴胡、龙骨、牡蛎、甘草、黄芩、党参、半夏、磁石、白芍、僵蚕、全蝎、桂枝、干姜;气郁化火证的核心组方是柴胡、地骨皮、天麻、玄参、桑白皮、桃仁、粉葛、石菖蒲、全蝎、车前子、远志、竹茹、天竺黄、伸筋草、木瓜、半夏。

关键词: 抽动障碍, 数据分析, 马融, 临床经验

Abstract: Objective To summarize the clinical experience of Professor Ma Rong in differential treatment for children with tic disorder.Methods The database of effective cases of tic disorder treated by Chinese medicine was established,and the data were analyzed by frequency distribution,cluster analysis and association rules.Results Professor Ma Rong identified the top 5 TCM syndrome types of tic disorder in children as hyperactivity of liver and wind,external wind,spleen deficiency and phlegm accumulation,spleen deficiency and liver hyperactivity,qi depression turning into fire.The frequency of drugs and the primary and secondary drug combinations of each syndrome type were screened and the core formula was obtained.Conclusion The core components for live and wind hyperactivity syndrome were Gastrodia, Unguia, cassia, scorpion, chrysanthemum, keel and oyster. The core components for exogenous wind induced syndrome were forsythia, licorice, mint, honeysuckle, Schizonepeta, scutellaria, asparagus, Fructus aurantii, platycodon, burdock seed and scorpion. The core components for spleen deficiency and phlegm accumulation syndrome are calamus, bile south star, Fructus aurantii, pinellia, poria, tangerine peel, licorice, Chuanxiong, gastrodia, scorpion, Chloriti lapis, Lapis chloriti lapis, Radix nochiae and codonopsis. The core ingredients for spleen deficiency and liver hyperactivity syndrome were bupleurum, keel, oyster, licorice, scutellaria, codonopsis, pinellia, magnet, paeony, rigid silkworm, scorpion, nnamon twig and dried ginger.The core ingredients for Qi depression turning into fire syndrome were bupleurum, ground bone bark, gastrodia, scrophulariae, mulberry bark, peach kernel, pink kudu, calamus, scorpion, psyllium, polygonum, bamboo ,  pogon, Rhizoma japonica, papaya and pinellia.

Key words:

Tic disorder, Data analysis, Ma Rong, Clinical experience