关键词: 难治性喘息, 纤维支气管镜, 儿童

Abstract:
Objective
To find the cause of refractory wheezing by performing fiberoptic bronchoscopy in 82 children with such disease.
Methods
Totally 82 children with refractory wheezing in Hunan Children's Hospital from November 2013 to January 2016 were included as the subjects. The results of their fiberoptic bronchoscopy, etiology and complications were analyzed.
Results
A total of 82 children with refractory wheezing were examined by fiberoptic bronchoscopy，which showed that there were 30 cases of laryngomalacia，3 cases of congenital epiglottis cyst， 2 cases of subglottic scar formation and glottic insufficiency，1 case of congenital laryngeal web and 1 case of subglottic neoplasia. Trachea-bronchial abnormalities included 26 cases of tracheomalacia，1 case of papilloma of trachea，23 cases of trachea-bronchial stenosis，15 cases of trachea-bronchial foreign body，3 cases of tracheal bronchus，2 cases of bridging bronchus and 1 case of tracheoesophageal fistula. Totally 78 children underwent fiberoptic bronchoscopy and bronchoalveolar lavage fluid was obtained and cultured; bacterial culture was positive in 27 cases(34.6%)， and fungal culture was positive in 11 cases(14.1%). The most common complications of fiberoptic bronchoscopy were hypoxia and transient decline of heart rate; 5 cases had fever after operation.
Conclusion
Fiberoptic bronchoscopy is of great significance to the children with  refractory wheezing.

Key words: Refractory wheezing, Fiberoptic bronchoscopy, Children