ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2009, Vol. 1 ›› Issue (4): 307-309.

• 论著 • 上一篇    下一篇

新生儿肠外营养相关性胆汁淤积危险因素分析

  

  1. 527300 广东 云浮,云浮市妇幼保健院儿科(李金嫦);526020 广东 肇庆,肇庆市端州区妇幼保健院妇产科(黎翠芳);526100 广东 高要,高要市妇幼保健院儿科(杨春梅)
  • 出版日期:2009-08-25 发布日期:2019-06-12
  • 作者简介:李金嫦(1973-),女,主治医师。研究方向:儿科临床及科研工作,Email:lichang@163.com。

  • Online:2009-08-25 Published:2019-06-12

摘要: 目的分析危重症新生儿肠外营养相关性胆汁淤积(PNAC)的危险因素。
方法对接受肠外营养(PN)支持超过14 d的116例新生儿的临床资料进行回顾性分析,分析其发生PNAC的危险因素。
结果116例中发生PNAC 31例(26.7%),分析结果显示胎龄、出生体质量、PN持续时间和感染与PNAC等有密切相关。其中PN持续时间是PNAC的独立高危因素。
结论PN持续时间越长,发生PNAC的危险性越大,尽早肠内喂养,缩短PN时间,是降低PNAC的重要措施。

关键词: 婴儿, 新生, 疾病, 肠外营养, 胆汁淤积, 肺炎, 新生儿肺透明膜病

Abstract: ObjectiveTo analyze the risk factors of parenteral nutritionassociated cholestasis(PNAC) in highrisk neonates.MethodsA total of 116 cases who had accepted parenteral nutrition during the neonatal period for at least 14 days were included in this study.The risk factors of PNAC were analyzed.ResultsThe incidence of PNAC was 26.7%.Gestational age,birth weight,persistence time in PN and infection were all closely correlated with PNAC.The pesistance time in PN was an independent risk factor of PNAC.ConclusionThe longer the persistence time,the more risk of happening of PNAC.Early enteral feeding and shortening the time of PN are the important measures to lower the incidence of PNCA.

Key words: Infant,newborn/disease, Parenteral nutrition, Cholestasis, Pneumonia, Hyaline membrane disease in neonates