ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (6): 557-559.doi: 10.3969/j.issn.1674-3865.2016.06.001

• 临床论著 •    下一篇

醒脾养儿颗粒和硫酸镁联合治疗婴幼儿毛细支气管炎疗效观察

卢清国， 何明生，幸耀花，张敏，刘万芬，黄迎九   

  1. 332400 江西 九江，江西省修水县妇幼保健院儿科
  • 出版日期:2016-12-25 发布日期:2018-11-19
  • 通讯作者: 卢清国，E-mail：13979263215@163.com
  • 作者简介:卢清国(1972-)，男，副主任医师。研究方向：小儿呼吸系统疾病诊断及治疗
  • 基金资助:
    江西省卫生计生委中医药科研基金项目(2015A010)

Xinpi Yang'er granules combined with magnesium sulfate in the treatment of infantile capillary bronchitis

LU Qingguo，HE Mingsheng，XING Yaohua，ZHANG Min，LIU Wanfen，HUANG Yingjiu   

  1. Jiangxi Xiushui County Maternal and Child Health Care Hospital，Jiujiang 332400，China
  • Online:2016-12-25 Published:2018-11-19

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摘要： 目的：探讨醒脾养儿颗粒和硫酸镁联合治疗婴幼儿毛细支气管炎的治疗作用。
方法：2015年6月至2016年6月江西省修水县妇幼保健院儿科收治住院的婴幼儿毛细支气管炎320例，随机分为利巴韦林组、利巴韦林＋硫酸镁组、利巴韦林＋醒脾养儿颗粒组、利巴韦林＋醒脾养儿颗粒＋硫酸镁组4组，每组80例。4组患儿根据病情给予吸氧、止咳化痰、雾化平喘等基础治疗，治疗5～7 d。观察治疗效果、症状体征消失时间、住院时间及不良反应。
结果：利巴韦林组、利巴韦林＋硫酸镁组、利巴韦林＋醒脾养儿颗粒组总有效率分别为71.3%(57/80)、72.5%(58/80)、73.8%(59/80)，低于利巴韦林＋醒脾养儿颗粒＋硫酸镁组90.0%(72/80)，差异有统计学意义(P<0.008 3)。利巴韦林＋醒脾养儿颗粒＋硫酸镁组患儿症状体征消失时间及住院时间均短于其他3组，差异有统计学意义(P<0.05)。4组患儿均未发生不良反应。
结论：醒脾养儿颗粒和硫酸镁联合治疗婴幼儿毛细支气管炎可缩短疗程、缓解临床症状、疗效确切、方便安全。

关键词: 毛细支气管炎, 醒脾养儿颗粒, 硫酸镁, 中西医结合疗法, 婴幼儿

Abstract: Objective:To study the effect of Xingpi Yang'er granules combined with magnesium sulfate in the treatment of infantile capillary bronchitis.
Methods:A total of 320 cases of infantile capillary bronchitis were hospitalized for treatment in Xiushui County Maternal and Child Health Care Hospital from June 2015 to June 2016, who were randomly divided into four groups,with 80 cases in each group: ribavirin group(A),ribavirin+magnesium sulfate group(B),ribavirin+Xingpi Yang'er granules group(C) and ribairin+Xingpi Yang'er granules+magnesium sulfate group（D）.Elementary treatment was given to the 4 groups of infants according to their conditions, including inhaling oxygen, reducing sputum, and relieving wheezing, which lasted five to seven days. Observe the treatment effect, adverse reactions, length of hospital stay and time for signs and symptoms to disappear.
Results：The total effective rate of group A，B and C was 71.3%(57/80)，72.5%(58/80) and 73.8%(59/80) respectively,which was lower than that of group D(90.0%,72/80), and the difference was of statistical significance(P<0.008 3).The time for signs and symptoms to disappear and the length of hospital stay were shorter in group D than the other 3 groups, and there was statistical difference(P<0.05).There was no adverse reactions in all the 4 groups.
Conclusion：The treatment of Xingpi Yang'er ganules combined with magnesium sulfate for infantile capillary bronchitis can shorten the treatment course and relieve clinical symptoms, which is effective, safe and convenient.

Key words: Capillary bronchitis, Xingpi Yang'er granules, Magnesium sulfate, Combined therapy of traditional Chinese and western medicine, Infants and young children