Abstract:
Objective
To explore the diagnostic value of clinical testing in the treatment of children with Mycoplasma pneumoniae infection.
Methods
A total of 90 children with Mycoplasma pneumoniae infection admitted to the Children's Hospital of Zhengzhou University from March 2017 to November 2018 were selected as observation group. Meanwhile,90 children receiving health examination in our hospital were selected as the control group. The blood of the two groups of children was collected for testing. The serum immunoglobulin, erythrocyte immune status and peripheral T lymphocyte subsets were analyzed and compared.
Results
There was no significant difference in IgG levels between the two groups(P>0.05). The level of IgM in the observation group was significantly higher than that in the control group, while the level of IgA was significantly lower, the difference being statistically significant(P<0.05). The RBCICR, immune adhesion promoting factor and RBC-C3bR in the observation group were significantly lower than those in the control group, while the immunoadhesive inhibitory molecules were significantly higher, the difference being statistically significant(P<0.05). CD3+, CD4+ and CD4+/CD8+ in the observation group were significantly lower than those in the control group, while CD8+ was significantly higher, and the difference was statistically significant(P<0.05).
Conclusion
The immune function of the children with Mycoplasma pneumoniae infection is affected. The serum immunoglobulin, erythrocyte immune status and peripheral blood T lymphocyte status of these children are lower than those of healthy children. Therefore, the children's immune function should be paid attention to during treatment.

Key words: Mycoplasma pneumoniae infection, Serum immunoglobulin, Erythrocyte immunity, Peripheral blood T lymphocyte subsets, Children