Abstract: Objective:To explore the correlation of neutrophil/lymphocyte ratio(NLR) and mean platelet volume/platelet count ratio(MPR) with febrile seizures.
Methods:A total of 103 children with febrile seizures who were admitted to Baotou Central Hospital from October 2019 to December 2020 were selected as the observation group, and 109 children with acute upper respiratory tract infection who had fever without seizures were selected as the control group. The blood cells and electrolytes of the two groups were analyzed respectively, and the NLR and MPR values were calculated.
Results:The NLR and MPR of the observation group were significantly higher than those of the control group, and the difference was statistically significant (P<0.05). The blood potassium and sodium of observation group were lower than those of the control group, and the difference was statistically significant (P<0.05); there was no statistically significant difference in blood chloride or calcium between the two groups(P>0.05). The ROC curves of NLR and MPR indicated that the best critical value of NLR was 3.79, the sensitivity was 80.6%, and the specificity was 56.0%; the best critical value of MPR was 0.032 55, the sensitivity was 72.8%, and the specificity was 53.2%.
Conclusion:NLR and MPR are correlated with febrile seizures. At the same time, changes in serum electrolytes may also be an important cause of febrile seizures, among which blood sodium and potassium are lowered.
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Key words: Febrile seizures, Neutrophil/lymphocyte ratio, Mean platelet volume/platelet count ratio, Children