Abstract:

Objective To investigate the efficacy of Chinese medicine bathing as adjuvant therapy for neonatal hyperbilirubinemia of different etiologies.Methods A total of 322 infants hospitalized for neonatal hyperbilirubinemia from September 2018 to October 2020 were selected and were divided into two groups:observation group (161 cases) and control group (161 cases)，by random number table method according to different etiologies.Blue light irradiation was used in the control group，and TCM bathing was used in the observation group in addition to the treatment for the control group.The changes of serum total serum bilirubin(TSB)，average daily stool frequency，phototherapy time and efficacy were observed before treatment，48h after treatment and at the end of treatment.Results There was a significant difference in the average number of bowel movement per day between the two groups(P<0.05)，while there was no significant difference in the duration of phototherapy(P>0.05) or the short-term efficacy(P>0.05).TSB at the end of treatment in both groups had statistical significance for breast milk jaundice(P<0.05).The decline of TSB with different etiologies was different in the observation group with treatment time increasing(P<0.05).There were differences between the causes of G-6-PD deficiency and other causes at 48h after treatment (P<0.05)，and also between the causes of G-6-PD deficiency and breast milk jaundice and perinatal high-risk factors at the end of treatment (P<0.05).Conclusion Chinese medicine bathing as adjuvant therapy for neonatal hyperbilirubinemia has the same short-term efficacy as blue light irradiation alone.However，Chinese medicine bathing as adjuvant therapy is more effective for breast milk jaundice，while for G-6-PD deficiency jaundice it is relatively less effective than other etiologies.

Key words:

Hyperbilirubinemia;Traditional Chinese medicine bathing;Blue light irradiation;Total serum bilirubin;Infant, newborn