ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2021, Vol. 13 ›› Issue (6): 537-540.doi: 10.3969/j.issn.1674-3865.2021.06.020

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Efficacy of Jiedu Kaiqiao decoction combined with western medicine on purulent meningitis in children

GUAN Xiaolei   

  1. Rehabilitation Department of Pingdingshan First People's Hospital,Pingdingshan 467000,China

  • Received:2021-01-07 Published:2021-12-25 Online:2021-12-25
  • Contact: GUAN Xiaolei,E-mail:pkxngg@163.com

Abstract: Objective To explore the efficacy of Jiedu Kaiqiao decoction combined with western medicine on purulent meningitis in children.Methods A total of 122 children with purulent meningitis admitted to this hospital between August 2018 and September 2020 were selected, and they were randomly divided into the experimental group(61 cases, Jiedu Kaiqiao decoction combined with meropenem dripping) and the control group(61 cases, meropenem dripping).The treatment course was one week. The total effective rate, protein level, white blood cell count, cerebrospinal fluid pressure, procalcitonin(PCT), C-reactive protein(CRP) and tumor necrosis factor-α(TNF-α) were compared between the two groups.Results The total effective rate was 95.08% in the experimental, which was higher than that of the control group(81.97%)(P<0.05). After treatment the level of protein, white blood cell count,cerebrospinal fluid pressure and the levels of PCT, CRP and TNF-α of experiment group were all lower than those of the control group(P<0.05).Conclusion Jiedu Kaiqiao decoction combined with meropenem can help relieve the inflammatory response and cerebrospinal fluid pressure, and reduce the white blood cell count and protein level of children with purulent meningitis, with significant clinical efficacy.

Key words:

Purulent meningitis, Jiedu Kaiqiao decoction, Children