ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2015, Vol. 7 ›› Issue (5): 491-495.doi: 10.3969/j.issn.1674-3865.2015.05.030

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Research on the effect of seretide combined with budesonide and leukotriene in the treatment of children with cough variant asthma

GUO Yuxiu, QIN Dalie, LI Jun   

  1. Baise People's Hospital,Baise 533000,China.
  • Online:2015-10-25 Published:2015-11-19

Abstract:
Objective:
To summarize the treatment effect of seretide combined with budesonide and leukotriene receptor antagonist on children with cough variant asthma.
Methods:Totally 120 cases of children with cough variant asthma were divided into observation group (62 cases) and control group (58 cases) according to the number of visits (the last odd and even number), and were given the routine treatment. Besides, the control group were given seretide and budesonide treatment; the observation group were given seretide,budesonide and leukotriene receptor antagonist (montelukast) treatment;analyze the effect in the two groups.
Results:The pulmonary ventilation function of the two groups were improved after treatment, and the observation group was better than the control group (P<0.05); the level of IL-4, IL-10 and IL-13 of two groups were improvd after treatment, and the observation group was obviously better than the control group (P<0.05); the clinical effect of the observation group was obviously better than that of the control group (P<0.05),with a statistical significance.
Conclusion: Seretide combined with budesonide and leukotriene receptor antagonist agent has remarkable effect in the treatment of children with cough variant asthma with high security, and is worthy to be popularized.

Key words: cough variant asthma, seretide/therapeutic use, montelukast/therapeutic use, budesonide/therapeutic use, children

CLC Number: