Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2013, Vol. 5 ›› Issue (1): 5-8.doi: 10.3969/j.issn.1674-3865.2013.01.002
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SUN Yingying,SUN Liping.
Online:
Published:
Abstract: Objective:To discuss the Yiqi Guben capsule role in regulating the splenic lymphocyte proliferation of lungQi deficiency mice. Methods:Totally 96 mice (male and female in half) were equally divided into 6 groups: normal control group, model group, Yiqi Guben capsules highdose group, middledose group and lowdose group, control group of Yupingfeng powder. Apart from the normal group, the mice in the rest of each group were made into lungQi deficiency syndrome models by adopting improved smoked method; tested drugs were given by intragastric administration for five weeks; XTT method was taken to assay the proliferation of splenic lymphocyte stimulated by the LSP or ConA. Results:After lungQi deficiency modeling,the function of the splenic B and T lymphocyte proliferation was significantly lower than the normal control group (P<0.001);after the tested drugs were given by intragastric administration, the function of splenic B and T lymphocyte proliferation was significantly increased; compared with the model group, the splenic lymphocyte proliferation function of control group, of Yupingfeng powder group, of Yiqi Guben capsule highdose group and middledose group was significantly increased(P<0.05),and the increase of Yiqi Guben capsule highdose group was the most significant. Conclusions:Yiqi Guben capsule can improve the lymphocyte proliferation activity of lungQi deficiency mice,thereby regulate the immune function.
SUN Yingying,SUN Liping. . The experimental study of Yiqi Guben capsule in adjusting the splenic lymphocyte proliferation of lungQi deficiency mice[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2013, 5(1): 5-8.
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