ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2015, Vol. 7 ›› Issue (5): 494-497.doi: 10.3969/j.issn.1674-3865.2015.05.031

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The diagnostic value of brain natriuretic peptide (BNP) in infants with severe pneumonia complicated with heart failure

HE Leifeng, YANG Ying, LIU Zhongqi, TAN Runguo, WANG Jinghui, DU Qiuping, CHEN Xianghong   

  1. Zhengzhou First People's Hospital,Zhengzhou 450004,China.
  • Online:2015-10-25 Published:2015-11-19

Abstract: ObjectiveTo summarize the value of brain natriuretic peptide (BNP) in the diagnosis of severe pneumonia complicated with heart failure in infants.MethodsIn 100 cases of children clinically diagnosed with common pneumonia (group A) and 100 cases of children with severe pneumonia complicated with heart failure (group B)and 80 cases of children with severe pneumonia (no heart failure) group (C),the laboratory results were retrospectively analyzed.ResultsIn the three groups of children the abnormal rate of CK, CKMB (creatine kinase, creatine kinase isoenzyme), CTNI (troponin) and BNP had significant difference (P<0.01); further comparison showed that befween group A and group B serum CK, CKMB, CTNI and BNP were significantly different (P<0.01)in abnormal rate; between group A and group C abnormal rate of serum BNP had no obvious difference (P>0.05), but abnormal rate of CK, CKMB and CTNI of had obvious difference (P<0.01); between group B and group C abnormal rate of CK, CKMB and CTNI had no significant difference (P>0.05), but abnormal rate of BNP had obvious difference (P<0.01); in group B, after heart failure was corrected, BNP was restored to normal range.ConclusionBNP is a sensitive and special objective marker for infants with severe pneumonia complicated with heart failure.

Key words: pneumonia/complication, heart failure/complication, BNP/treatment application, children

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