ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2025, Vol. 17 ›› Issue (2): 121-125.doi: 10.20274/j.cnki.issn.1674-3865.2025.02.005

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母乳中母乳低聚糖对婴儿肠道菌群的影响及研究进展

李建英, 薛玲艳, 贺春兰, 赵玲莉   

  1. 810001 青海 西宁,青海大学附属医院检验科

  • 收稿日期:2024-12-25 出版日期:2025-04-25 上线日期:2025-04-25
  • 通讯作者: 贺春兰,E-mail:502435727@qq.com;赵玲莉,E-mail:Zhaolingli640521@163.com
  • 基金资助:
    青海省科技计划项目(2024 ZJ 772)

Effects of human milk oligosaccharides in breast milk on intestinal flora of infants and research progress

LI Jianying,XUE Lingyan,HE Chunlan,ZHAO Lingli   

  1. Affiliated Hospital of Qinghai University,Xining 810001,China

  • Received:2024-12-25 Published:2025-04-25 Online:2025-04-25
  • Contact: HE Chunlan,E-mail:502435727@qq.com;ZHAO Lingli,E-mail:Zhaolingli640521@163.com

摘要: 母乳中的母乳低聚糖可有效促进婴儿肠道中有益细菌群的生长和定植,抑制病原菌的侵袭。通过改善婴儿肠道菌群组成,提高肠道菌群的丰度,维持婴儿肠道健康,增强婴儿的免疫系统,对肠道功能紊乱相关性疾病也有预防作用。本文主要阐述了近几年母乳低聚糖与婴儿肠道菌群相关性的研究进展,总结了母乳低聚糖在母体内受母体基因型等因素影响,进一步探讨母乳低聚糖对婴儿肠道菌群的促进作用,对更好还原母乳营养成分喂养和预防相关疾病有重要意义。


关键词: 母乳, 母乳低聚糖, 肠道菌群, 儿童

Abstract: Human milk oligosaccharides (HMOs) in breast milk can effectively promote the growth and colonization of beneficial bacteria in the infant's intestinal tract and inhibit the invasion of pathogenic bacteria.By improving the composition of the infant's intestinal flora and increasing the abundance of the intestinal flora,it maintains the health of the intestinal tract and enhances the immune system of infants,and also has an significant preventive effect on intestinal dysfunction related diseases.This article mainly expounds the research progress in the correlation between HMOs and the infant's intestinal flora in recent years,summarizes the influence of factors such as the mother's genotype on HMOs in the mother's body,and further explores the promoting effect of HMOs on the infant's intestinal flora,which is of great significance for better restoring the nutritional components of breast milk for feeding and preventing related diseases.


Key words: Breast milk, Human milk oligosaccharides, Intestinal flora, Child