ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2009, Vol. 1 ›› Issue (3): 208-209.doi: 10.3969/j.issn.1674-3865.2009.03.002

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小儿利咽康颗粒剂抗炎作用的实验观察

宋光熠，王实，张广新，刘永林，李开明   

  1. 110101 沈阳，辽宁中医药大学职业技术学院医学基础部
  • 收稿日期:2009-03-23 出版日期:2009-06-25 上线日期:2009-06-25
  • 通讯作者: 闵晓兰
  • 作者简介:闵晓兰（1975-），女，主治医师。研究方向：小儿内科疾病的治疗。

Analysis of the diagnostic course and diagnosis result of 386 cases of neonatal convulsion

SONG Guang yi,WANG Shi,ZHANG Guang xin   

  1. Department of Basic Medical Sciences,College of Vocational Technology,Liaoning University of TCM，Shenyang 110101,China
  • Received:2009-03-23 Published:2009-06-25 Online:2009-06-25

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摘要： 目的：观察小儿利咽康颗粒剂的抗炎作用。方法：采用皮下注射5-羟色胺所致大鼠毛细血管通透性增加法、皮下注入角叉莱胶致大鼠足跖肿胀法、皮下埋藏无菌滤纸片致大鼠肉芽肿增生法，观察小儿利咽康颗粒剂的抗炎作用。结果：利咽康颗粒各剂量组对5-羟色胺所致毛细血管通透性、对角叉莱胶致大鼠足跖肿胀、对大鼠肉芽肿增生均有抑制作用。结论：小儿利咽康颗粒剂具有抗炎作用。

关键词: 利咽康颗粒；炎症；中草药/治疗；动物, 实验；大鼠, 近交系

Abstract: Objective：To research into the diagnostic course of convulsion which is in accordance with neonates' characteristics，thus reduce the diagnostic cost.Methods：The study population included 386 patients(189males and 197 females,mean age 7.5 days) with convulsion of unknown causes from October 2006 to June 2008.All patients were evaluated by strict diagnostic protocol in neonatal with convulsion.Results：By the initial evaluation diagnosis was clarified in 262 patients(262/386,67.9%).After further tests,a definite diagnosis was established in 91 patients(91/386,23.6%).After the whole diagnostic protocol,a definite diagnosis was established in 353 patients(353/386,91.5%)，undiagnosed patients，8.5%.Conclusion：The use of practical diagnostic protocol for neonatal convulsion results in higher etiological diagnosis rate，and it can properly guide the performance of the accessory examination，thus reduce the diagnostic cost.

Key words: Convulsions/Diagnose；Encephalopathy/Diagnose;Infant, newborn；Infant,preterm