ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2016, Vol. 8 ›› Issue (3): 322-324.doi: 10.3969/j.issn.1674-3865.2016.03.025

• 临床研究 • 上一篇    下一篇

热毒宁注射液治疗小儿咽结合膜热疗效观察

曹效红   

  1. 451200河南 巩义，巩义市人民医院儿科
  • 出版日期:2016-06-25 发布日期:2018-11-19
  • 作者简介:曹效红(1970-)，女，副主任医师。研究方向：小儿内科疾病的诊断治疗

Observation on the effect of Reduning injection in the treatment of children with pharyngoconjunctival fever

CAO Xiaohong   

  1. Department of Pediatrics,the People′s Hospital of Gongyi,Gongyi 451200,China.
  • Online:2016-06-25 Published:2018-11-19

PDF (PC)

114

摘要：
目的: 观察热毒宁注射液治疗小儿咽结合膜热的疗效及安全性。
方法: 将66例咽结合膜热患儿随机分成观察组与对照组各33例。对照组采用炎琥宁粉针剂治疗，每次0.08~0.2 g，加入250 mL 5%葡萄糖氯化钠注射液中静脉滴注，持续治疗3 d。观察组使用热毒宁注射液20 mL加入250 mL生理盐水注射液静脉滴注，每日1次，持续治疗4 d。疗程结束后比较两组治疗效果。
结果: 观察组总有效率为93.94%(31/33)，优于对照组66.67%（22/33)，差异有统计学意义(P<0.05)|观察组在临床退热、咽痛消失、眼结合膜充血消失及住院时间方面均优于对照组，差异有统计学意义(P<0.05)|观察组不良反应率为6.06%(2/33)，优于对照组27.27%（9/33)，差异有统计学意义(P<0.05)。
结论: 热毒宁注射液治疗小儿咽结合膜热效果显著，安全性高，临床具有实际推广价值。

关键词: 咽结合膜热, 热毒宁注射液/治疗应用, 儿童

Abstract:
Objective: To observe the effect and safety of Reduning injection in the treatment of children with pharyngoconjunctival fever.
Methods: A total of 66 cases of pharyngoconjunctival fever in children were selected and divided into two groups by random number table method:the observation group(33 cases) and the control group(33 cases).The control group received treatment of Yanhuning powder-injection,   0.08~0.29 each time,which was added to 250 mL of  5% glucose injection for intravenous dripping|the treatment lasted for 3 days.
Results: was used for treatment in the observation group, 20 mL of which was added to 250 mL of normal saline injection,once a day,and the treatment lasted for 4 days,Compare the treatment effect between the two groups at the end of the course.Results:The total effective rate was 93.94% in the observation group,which was better than of the control group(66.67%),the difference being of statistical significance(P< 0.05).The observation group was better than the control group in the following aspects:clinical abatemen of fever,disappearance of sore throat and pharyngoconjunctival congestion,and hospital stay,and there was statistical diffence between the two groups(P< 0.05).The rate of adverse reactions was 6.06% in the observation group,and it was better than than in the contril group(27.27%),the difference being statistical(P<0.05).
Conclusion: Reduning Injection has  great effect in the treatment of children with pharyngoconjunctival fever with high safety,which is of practical value of promotion in clinics.

Key words: Pharyngoconjunctival fever, Reduning injection/therapeutic use, Children