ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2017, Vol. 9 ›› Issue (2): 141-144.doi: 10.3969/j.issn.1674-3865.2017.02.016

• 临床研究 • 上一篇    下一篇

曲普瑞林激发试验对青春早发育女童的诊断价值

洪庆荣,顾绍庆,徐丽琴,叶元枫   

  1. 212002 江苏 镇江,镇江市第一人民医院儿科
  • 出版日期:2017-04-25 发布日期:2017-12-18
  • 通讯作者: 洪庆荣,E-mail:drhqr@163.com
  • 作者简介:洪庆荣(1969-),男,医学硕士,副主任医师。研究方向:小儿内分泌遗传代谢性疾病的诊治

Diagnostic value of triptorelin stimulation test for early puberty in girls

HONG Qingrong,GU Shaoqing,XU Liqin,YE Yuanfeng   

  1. Department of Pediatrics,The First People's Hospital of Zhenjiang,Zhenjiang 212002,China
  • Online:2017-04-25 Published:2017-12-18

摘要:
目的:评价曲普瑞林激发试验对青春早发育女童的诊断价值。
方法:分析2013年6月至2016年8月在镇江市第一人民医院儿科就诊的青春早发育女童47例及性早熟女童62例的曲普瑞林激发试验资料。
结果:以黄体生成素激发峰值>5.05 IU/L为诊断切点,青春早发育组与性早熟组诊断阳性率分别为89.4%(42/47)与90.3%(56/62),两组间诊断阳性率比较差异无统计学意义(P>0.05)。
结论:曲普瑞林激发试验对判断女童青春早发育的性质具有诊断价值,且大多数黄体生成素激发峰值在30~60 min出现。

关键词: 青春早发育, 曲普瑞林, 激发试验, 儿童

Abstract:
Objective:To assess the diagnostic value of triptorelin stimulation test for early puberty in girls.
Methods:Triptorelin stimulation test data were collected and analyzed in 47 girls with early puberty(EP group) and 62 girls with precocious puberty(PP group) in the Department of Pediatrics of the First People's Hospital of Zhenjiang between Jun.2013 and Aug.2016.
Results:Take peak luteinizing hormone level(>5.05 IU/L) as the diagnosis point, the sensitivity for diagnosing early puberty and precocious puberty was 89.4%(42/47) and 90.3%(56/62),respectively,there being no significant difference between two groups(P>0.05).
Conclusion:The triptorelin stimulation test is of value to the diagnosis of early puberty in girls. The peak luteinizing hormone value of triptorelin provocation stimulation mostly focuses on the time period of 30 to 60 min after overdose.

Key words: Early puberty, Triptorelin, Provocation test, Child