ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2018, Vol. 10 ›› Issue (6): 482-484.doi: 10.3969/j.issn.1674-3865.2018.06.007

• 专栏 • 上一篇    下一篇

肺炎支原体感染与支气管哮喘急性发作的相关性研究

胡凤阳   

  1. 110034 沈阳，沈阳市儿童医院内五病房
  • 出版日期:2018-12-25 发布日期:2019-03-25
  • 作者简介:胡凤阳（1983-），女，主治医师。研究方向：小儿呼吸系统和神经系统疾病的诊治，E-mail：3479499846@qq.com

Study on the correlation between Mycoplasma pneumoniae infection and acute attack of bronchial asthma

HU Fengyang   

  1. Shenyang Children's Hospital, Shenyang 110034, China
  • Online:2018-12-25 Published:2019-03-25

PDF (PC)

99

摘要：
目的
观察儿童肺炎支原体感染对支气管哮喘急性发作的影响，分析其相关性。
方法
选择2016年7月至2018年3月在沈阳市儿童医院收治支气管哮喘急性发作并发肺炎患儿54例为研究对象，为观察组；同期收治的肺炎患儿54例作为对照组。治疗后对两组检测血清MPIgM、血清IgE、外周血嗜酸性粒细胞指标。
结果
观察组患儿MPIgM阳性率为481%（26/54），显著高于对照组111%（6/54），差异有统计学意义（P<005）。MPIgM阳性患儿IgE及嗜酸性粒细胞计数显著高于MPIgM阴性患儿，差异有统计学意义（P<005）。
结论
肺炎支原体感染与支气管哮喘间存在密切联系，肺炎支原体感染可诱发支气管哮喘致患儿症状加重，可通过强化小儿支气管哮喘检查，检测相关指标，可有效及早进行诊断，在临床中具有广泛的应用价值，值得进一步推广。

关键词: 肺炎支原体感染, 支气管哮喘, 急性发作, 儿童

Abstract:
Objective
To analyze the influence of Mycoplasma pneumoniae infection on the acute attack of bronchial asthma in children.
Methods
A total of 54 patients with acute exacerbation of bronchial asthma and Mycoplasma pneumoniae infection in our hospital were included as the experimental group. Another 54 children with respiratory tract infection were used as the control group. After the treatment, serum mycoplasma antibodies(MP-IgM), serum IgE, and peripheral eosinophilic granulocyte markers were detected in both groups.
Results
Compared with the control group, the positive rate of MPIgM in the experimental group was significantly increased(11.1%,6/54) with significant difference(P<0.05). The level of serum IgE and positive EOS counts were significantly higher in the MP-IgM positive group than in the negative group(P<0.05).
Conclusion
There is a close relationship between Mycoplasma pneumoniae infection and pediatric bronchial asthma. Mycoplasma pneumoniae infection can induce bronchial asthma and exacerbate the symptoms of children. Strengthening pediatric bronchial asthma examination and detecting related indicators can help to effectively make an early   diagnosis and has a wide range of clinical and is worth further promotion.

Key words: Mycoplasma pneumoniae infection, Bronchial asthma, Acute attack, Children