关键词: 神经母细胞瘤, 化疗, 心力衰竭, 儿童

Abstract: One case of neuroblastoma complicated with heart failure in children is reported, and the possible cause was studied. The child patient is 3 years and 7 months old, the onset is occult and anorexia is the first symptom. After abdominal imaging and postoperative histopathological examination, it is diagnosed as neuroblastoma. In the 4 months of treatment, the following chemotherapy regimens have been used in turn: cyclophosphamide combined with irinotecan, etoposide combined with cisplatin， and then etoposide combined with nedaplatin. After 5 cycles of chemotherapy, the child has some symptoms of acute heart failure, including dyspnea, forced sitting position, pallor, cyanosis and irritation. Clinically there have been few reports on heart failure after chemotherapy for neuroblastoma, so we should be alert and pay attention to the toxic effect of chemotherapy medicines on heart, performing related examinations at an early stage in order to improve heart function and the prognosis.

Key words:

Neuroblastoma, Chemotherapy, Heart failure, Children