ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (1): 43-.

• 临床研究 • 上一篇    下一篇

低碘浓度对比剂对小儿先天性心脏病CTA图像质量的影响

陈聪聪，崔得金，孙利芳，郑彬   

  1. 450000 郑州，郑州大学附属儿童医院、河南省儿童医院、郑州儿童医院放射科
  • 出版日期:2021-02-25 发布日期:2021-05-17
  • 通讯作者: 陈聪聪，E-mail：bianresou19680212@163.com
  • 作者简介:陈聪聪(1988-)，女，医师。研究方向：CT及X线诊断，特殊造影检查诊断
  • 基金资助:
    2018年度河南省医学科技攻关计划（联合共建项目）（2018020620）

Effect of low iodine concentration contrast medium on image quality of CTA in children with congenital heart disease

CHEN Congcong, CUI Dejin, SUN Lifang, ZHENG Bin   

  1. Department of Radiology, Zhengzhou Children's Hospital，Zhengzhou 450000，China
  • Online:2021-02-25 Published:2021-05-17

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摘要： 目的:探讨低碘浓度对比剂对小儿先天性心脏病CTA图像质量的影响。
方法:选择2019年6月至2020年6月我院接收的确诊为小儿先天性心脏病患儿70例作为研究对象，随机分为低碘组和对照组各35例。对照组采用常规370 mgl/mL碘对比剂，低碘组采用低碘浓度270 mgl/mL对比剂。两组患儿均行冠状动脉CTA检查，图像采用滤过反摄影法进行重建，并比较两组CTA图像心腔、大血管CT值、CTA图像清晰度主观评分及对比剂均匀度评分。
结果:两组CTA图像心腔、大血管CT值对比，差异无统计学意义（P＞0.05）；低碘组大血管、心内结构、冠动脉起源等图像清晰度均高于对照组，差异有统计学意义（p＜0.05）；两组对比剂均匀度中，右心房与右心室相比较，差异无统计学意义（P＞0.05）。
结论:低碘浓度对比剂对小儿先天性心脏病诊断良好，能够获取高质量冠脉CTA图像，满足诊断需要，同时降低辐射剂量。

关键词: 先天性心脏病, 低碘浓度对比剂, CTA图像质量, 对比剂均匀度, 儿童

Abstract: Objective:To investigate the effect of low iodine concentration contrast medium on the image quality of CTA in children with congenital heart disease.
Methods:Totally 70 children with congenital heart disease diagnosed in our hospital from June 2019 to June 2020 were selected as the research subjects: 35 children receiving conventional iodine contrast medium(370 mgl/mL) were included in the control group, and 35 children receiving low iodine concentration iodine contrast medium(270 mgl/mL) were included in the low iodine group. Coronary CTA was performed in both groups, and the images were reconstructed by filtered back radiography (FBP). The CT values of cardiac cavity and large vessels, subjective score of CTA image clarity and contrast medium uniformity score were compared between the two groups.
Results:There was no significant difference in the CT value of cardiac cavity and large vessels between the two groups (P>0.05); the image clarity of large vessels, cardiac structure and origin of coronary artery in the low iodine group was higher than that in the control group(P<0.05); the uniformity of contrast medium was compared, and there was no significant difference between right atrium and right ventricle(P>0.05).
Conclusion:Low iodine concentration contrast medium is a good diagnostic method for congenital heart disease in children. It can obtain high-quality coronary CTA images, meet the needs of diagnosis, and reduce radiation dose.

Key words: Congenital heart disease, Low iodine concentration contrast medium, CTA image quality, Contrast medium uniformity, Children