ISSN 1674-3865  CN 21-1569/R
主管:国家卫生健康委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (2): 173-.

• 小儿中药应用研究 • 上一篇    下一篇

哮喘补益膏加减联合三伏贴治疗儿童哮喘缓解期临床观察

贾雪,金云姣,赵琼,廖敏,周鸿雲,刘茜玮   

  1. 610000 成都,成都中医药大学附属医院儿科(贾雪,赵琼);610000成都,成都市双流区中医院儿科(金云姣);610000 成都,四川省人民医院中医科(廖敏);450000郑州,河南中医药大学第一临床医学院儿科(周鸿雲);100000 北京,北京中医药大学(刘茜玮)
  • 出版日期:2021-04-25 发布日期:2021-05-18
  • 通讯作者: 赵琼,E-mail:823691452@qq.com
  • 作者简介:贾雪(1994-),女。研究方向:小儿脾胃疾病的中医药治疗
  • 基金资助:
    四川省中医药科学技术研究专项项目(2016Q002)

Clinical study of modified asthma tonifying ointment combined with Sanfu plaster in the treatment of childhood asthma in remission stage

JIA Xue,JIN Yunjiao,ZHAO Qiong,LIAO Min,ZHOU Hongyun,LIU Qianwei   

  1. Chengdu University of TCM,Chengdu 610000,China
  • Online:2021-04-25 Published:2021-05-18

摘要: 目的:观察哮喘补益膏加减联合三伏贴治疗儿童哮喘缓解期的临床疗效。
方法:选择2017年8月至2018年6月四川省中医院就诊的哮喘缓解期患儿70例为研究对象,随机分为对照组34例和观察组36例。对照组采用吸入用布地奈德混悬液及口服孟鲁司特钠咀嚼片治疗,观察组采用口服哮喘补益膏加减及三伏贴治疗。疗程3个月。治疗结束后,从哮喘症状控制水平、肺功能、中医症状积分、中医证候疗效、安全性方面对比两种方案的临床疗效。
结果:治疗结束后观察组脱落6例,对照组脱落4例。两组在哮喘症状控制水平和无喘息症状时间方面比较差异无统计学意义(P>0.05)。在肺功能方面,两组治疗后最大呼气流速峰值均低于治疗前,差异有统计学意义(P<0.05),治疗后两组最大呼气流速峰值比较差异无统计学意义(P>0.05)。观察组治疗后中医症状总积分低于对照组,差异有统计学意义(P<0.05)。观察组治疗后反复感冒次数、自汗、纳差、大便异常中医症状积分低于对照组,差异有统计学意义(P<0.05)。观察组总有效率为96.7%(29/30),显著高于对照组43.3%(13/30),差异有统计学意义(P<0.05)。在哮喘补益膏联合三伏贴对儿童哮喘缓解期肺脾气虚证的治疗期间、治疗结束后患儿均无明显不良反应。
结论:哮喘补益膏加减联合三伏贴治疗儿童哮喘缓解期的临床疗效效果好且用药安全。

关键词: 哮喘缓解期, 肺脾气虚证, 临床疗效, 安全性

Abstract: Objective:To observe the clinical efficacy of modified asthma tonifying ointment combined with Sanfu plaster in the treatment of children with asthma in remission stage.
Methods:A total of 70 children with asthma in remission stage treated from August 2017 to June 2018 in Sichuan Hospital of Traditional Chinese Medicine were selected and randomly divided into control group(n=34) and observation group(n=36).The control group was treated with inhaled budesonide suspension and oral montelukast sodium chewable tablets,while the observation group was treated with oral asthma tonifying ointment with modification and Sanfu plaster.The course of treatment was 3 months.After treatment,the clinical effects of the two schemes were compared in terms of control level of asthma symptoms,lung function,TCM symptom score,TCM syndrome efficacy and safety.
Results:After treatment,there were 6 cases lost in observation group and 4 in control group.There was no significant difference in the control level of asthma symptoms or the time of nonwheezing symptoms between the two groups(P>0.05).In terms of pulmonary function,the PEF values of the two groups after treatment were lower than those before treatment,and the difference was statistically significant(P<0.05);there was no significant difference in PEF value between the two groups after treatment(P>0.05).After treatment,the total score of TCM symptoms in the observation group was lower than that in the control group,and the difference was statistically significant(P<0.05).After treatment,the TCM symptom scores of repeated colds,spontaneous sweating,poor appetite and abnormal stool in the observation group were significantly lower than those in the control group(P<0.05).The total effective rate in the observation group was 96.7%(29/30),which was significantly higher than that in the control group(43.3%,13/30),and the difference was statistically significant(P<0.05).There was no obvious adverse reaction during and after treatment with asthma tonifying ointment combined with Sanfu plaster for lung and spleen qi deficiency syndrome in children with asthma in remission stage.
Conclusion:Modified asthma tonifying ointment combined with Sanfu plaster is effective and safe in the treatment of children with asthma in remission stage.

Key words: Asthma in remission stage, Lung-spleen qi deficiency, Clinical efficacy, Safety