ISSN 1674-3865  CN 21-1569/R
主管：国家卫生健康委员会
主办：中国医师协会
　　　辽宁省基础医学研究所
　　　辽宁中医药大学附属医院
中国中西医结合儿科学

中国中西医结合儿科学 ›› 2025, Vol. 17 ›› Issue (2): 93-98.doi: 10.20274/j.cnki.issn.1674-3865.2025.02.001

• •    下一篇

敷胸散辅助治疗儿童肺炎支原体肺炎的多中心临床研究

沈红岩, 张秀英, 谭春迎, 尚涛, 孟斌, 穆婧雯, 田智帆, 鄂明欣, 王雪峰   

  1. 110032 沈阳，辽宁中医药大学附属医院儿科（沈红岩，张秀英，王雪峰）；110005 沈阳，辽宁省妇幼保健院儿科（谭春迎）；112399 辽宁 开原，开原市中医医院儿科（尚涛）；117110 辽宁 本溪，本溪满族自治县中医院儿科（孟斌）；110847 沈阳，辽宁中医药大学中医儿科学专业研究生（穆婧雯，田智帆，鄂明欣）

  • 收稿日期:2025-02-10 出版日期:2025-04-25 上线日期:2025-04-25
  • 通讯作者: 王雪峰，E-mail：lnzywxf@163.com
  • 基金资助:
    国家传承创新中心重点病种项目（2023-247）；基于重点研究室研究领域的中医药多学科研究能力提升项目（2022-304）；王雪峰全国名老中医药专家传承工作室建设项目（国中医药人教发〔2022〕75号）

A multi center clinical study on the adjuvant treatment with Fuxiong powder for children with Mycoplasma pneumoniae pneumonia

SHEN Hongyan1，ZHANG Xiuying1，TAN Chunying2，SHANG Tao3，MENG Bin4，MU Jingwen5，TIAN Zhifan5，E Mingxin5，WANG Xuefeng1   

  1. 1Affiliated Hospital of Liaoning University of Traditional Chinese Medicine，Shenyang 110032，China;
    2Liaoning Provincial Maternal and Child Health Hospital，Shenyang 110005，China;3Kaiyuan Hospital of Traditional Chinese Medicine，Kaiyuan 112399,China;4Benxi Manchu Autonomous County Hospital of Traditional Chinese Medicine,Benxi 117110,China;5Liaoning University of Traditional Chinese Medicine,Shenyang 110847，China

  • Received:2025-02-10 Published:2025-04-25 Online:2025-04-25
  • Contact: WANG Xuefeng，E-mail：lnzywxf@163.com

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摘要： 目的:评价敷胸散辅助治疗儿童肺炎支原体肺炎（痰热闭肺证）的临床疗效与安全性。方法:选择2024年10月至2025年1月在辽宁中医药大学附属医院、辽宁省妇幼保健院、本溪满族自治县中医院、开原市中医医院收治的120例肺炎支原体肺炎（痰热闭肺证）患儿为研究对象，按患者意愿分为观察组和对照组各60例。对照组应用西医基础治疗，观察组在西医基础治疗上加以敷胸散穴位贴敷。疗程7 d。比较两组患儿的疾病临床疗效、临床症状缓解时间、肺部体征（啰音）消失时间、中医证候积分和不良反应。结果:两组患儿治疗后观察组愈显率为72%-22%（39/54），总有效率为92%-59%（50/54），均分别高于对照组50%-91%（28/55），83%-64%（46/55），观察组临床疗效优于对照组，差异有统计学意义（P<0.05）。观察组临床症状（咳嗽、喉间痰鸣、气促）缓解时间、肺部体征（啰音）消失时间均少于对照组，差异有统计学意义（P<0.05）。两组中医证候积分较治疗前均降低，且观察组优于对照组，差异均有统计学意义（P<0.05）。两组不良事件发生率比较差异无统计学意义（P>0.05）。结论:敷胸散辅助治疗儿童肺炎支原体肺炎（痰热闭肺证）具有较好临床疗效，可有效促进啰音吸收，改善咳嗽、喉间痰鸣、气促症状，且安全性好。 


关键词: 肺炎支原体肺炎, 中医外治法, 敷胸散, 儿童

Abstract: Objective:To evaluate the clinical efficacy and safety of Fuxiong powder in the adjuvant treatment of Mycoplasma pneumoniae pneumonia（phlegm-heat closing lung syndrome） in children.Methods:Totally 120 children with Mycoplasma pneumoniae pneumonia（phlegm-heat closing lung syndrome） were selected as the study subjects,who were admitted to the Affiliated Hospital of Liaoning University of Traditional Chinese Medicine，Liaoning Provincial Maternal and Child Health Hospital，Benxi Manchu Autonomous County Hospital of Traditional Chinese Medicine and Kaiyuan Hospital of Traditional Chinese Medicine from October 2024 to January 2025，and they were divided into two groups according to their wishes:60 cases in the experimental group and 60 cases in the control group.The control group was treated with basic treatment with western medicine，and the experimental group was treated with Fuxiong powder in addition to the basic treatment with western medicine.The course of treatment was 7 d.The clinical efficacy，time to remission of main symptoms，disappearance time of pulmonary signs（rales），TCM syndrome scores and adverse reactions were compared between the two groups.Results:After treatment，the healing and improvement rate of experimental group was 72%-22% (39/54),and the total effective rate was 92%-59% (50/54),both of which were higher than the control group ［(50%-91%,28/55）and (83%-64%,46/55)］,showing that the clinical efficacy of the experimental group was better than that of the control group (P<0.05).The relief time of clinical symptoms（cough，wheezing due to retention of phlegm in the throat，shortness of breath） and the disappearance time of pulmonary signs (rales) in the experimental group were both less than those in the control group (P<0.05).The TCM syndrome score was lower than before treatment in both groups，and the experimental group was better than the control group (P<0.05).There was no significant difference in the incidence of adverse events between the two groups（P>0.05）.Conclusion:The adjuvant treatment for Mycoplasma pneumoniae pneumonia（phlegm-heat closing lung syndrome） in children with Fuxiong powder has a good clinical efficacy，which can effectively promote rales absorption and improve the symptoms of cough,wheezing due to retention of phlegm in the throat and shortness of breath，and is safe. 

Key words: Mycoplasma pneumoniae pneumonia, Traditional Chinese medicine external treatment method, Fuxiong powder, Child