学龄前肥胖儿童肠道菌群分布特点及其相关因素分析

中国中西医结合儿科学 ›› 2021, Vol. 13 ›› Issue (1): 69-.

学龄前肥胖儿童肠道菌群分布特点及其相关因素分析

赵丹

450053 郑州，郑州市第九人民医院检验科

出版日期:2021-02-25 发布日期:2021-05-17
通讯作者: 赵丹，E-mail：zhao_dan1989@163.com
作者简介:赵丹（1989-），女，医学硕士，检验师。研究方向：医学检验

Distribution characteristics of intestinal flora in obese preschool children and the factors related to obesity

ZHAO Dan

Department of Laboratory Medicine, Zhengzhou Ninth People's Hospital, Zhengzhou 450053, China

Online:2021-02-25 Published:2021-05-17

摘要/Abstract

摘要： 目的：分析学龄前肥胖儿童肠道菌群分布特点，并研究学龄前儿童肥胖的相关因素。
方法：选取2019年7～12月于本院进行体检的学龄前肥胖儿童60例，为观察组，同期采用整群抽样法按照1∶2配比抽取健康儿童120例为健康对照组，检测两组儿童肠道菌群并进行对比分析，使用单因素和多因素回归分析研究学龄前儿童肥胖的相关因素。
结果：观察组肠道内变形杆菌水平显著高于健康对照组，双歧杆菌水平显著低于健康对照组，差异有统计学意义（P<0.05）。单因素分析显示，出生体质量、睡眠时间、进食速度、运动量、喂养方式、父母是否肥胖、饮食嗜好均是学龄前儿童肥胖的相关因素（P<0.05）；多因素分析显示，进食速度、运动量、喂养方式、父母是否肥胖及饮食嗜好均是学龄前儿童肥胖的影响因素（P<0.05）。
结论：应根据影响学龄前儿童的危险因素对其饮食情况进行有效干预，以降低学龄前儿童肥胖的发病率。

关键词: 肥胖, 肠道菌群, 危险因素, 学龄前儿童

Abstract: Objective：To analyze the distribution characteristics of intestinal flora in obese preschool children, and study the related factors of obesity in preschool children.
Methods：A total of 60 obese preschool children receiving physical examination in the hospital between July and December 2019 were selected as the observation group. Meanwhile, 120 healthy children were selected as the healthy control group by cluster sampling method. Intestinal floras of the two groups were detected and comparatively analyzed. Univariate analysis and multivariate regression analysis were performed to study the factors related to obesity in preschool children.
Results：The level of Proteobacteria in intestines of the observation group was significantly higher than that in the healthy control group, and the level of Bifidobacterium was significantly lower than that in the healthy control group(P<0.05). Univariate analysis showed that birth weight, sleep time, eating speed, exercise amount, feeding pattern, obesity of parents, and dietary habits were factors related to obesity in preschool children(P<0.05). Multivariate analysis showed that eating speed, exercise amount, feeding pattern, obesity of parents and dietary habits were influencing factors of obesity in preschool children (P<0.05).
Conclusion：Effective interventions for diets of preschool children should be carried out based on the risk factors to reduce the incidence of obesity in preschool children.

Key words: Obesity, Intestinal flora, Risk factor, Preschool children

赵丹. 学龄前肥胖儿童肠道菌群分布特点及其相关因素分析[J]. 中国中西医结合儿科学, 2021, 13(1): 69-.

ZHAO Dan. Distribution characteristics of intestinal flora in obese preschool children and the factors related to obesity[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(1): 69-.

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