中药和西药治疗儿童流行性感冒的成本-效果分析

doi:10.20274/j.cnki.issn.1674-3865.2025.05.010

Abstract

Abstract:

Objective To compare the cost-effectiveness of Xiaoer Feire Kechuan granules（XFK）with that of oseltamivir phosphate granules in the treatment of pediatric influenza to evaluate their economic value. Methods A decision tree model was developed from the perspective of the healthcare system to conduct a cost-effectiveness analysis. Univariate and probabilistic sensitivity analyses were performed to evaluate how parameter variations influenced the study outcomes. Results The incremental cost-effectiveness ratio(ICER) of XFK compared to oseltamivir phosphate granules was ￥96.8. The probabilistic sensitivity analysis results showed that over a 5-day treatment cycle, when the willingness-to-pay(WTP) exceeded ￥260, XFK became the more cost-effective option. Univariate sensitivity analysis indicated that the price of oseltamivir phosphate granules was the most sensitive factor among all the factors of ICER. Conclusion When the willingness-to-pay is over ￥260, XFK demonstrates a cost-effective advantage in the treatment of pediatric influenza.

Key words: Influenza, Xiaoer Feire Kechuan granules, Oseltamivir phosphate granules, Cost-effectiveness analysis, Child

CLC Number:

R725.6

Wei SHAO, Xifan MEI, Feng WANG, Fei YU, Sunjun YIN, Dan HAN. Cost-effectiveness analysis of traditional Chinese medicine and western medicine in the treatment of influenza in children[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2025, 17(5): 418-423.

Figures/Tables 7

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References 31

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指标	小儿肺热咳喘颗粒
指标	最小值	基础值	最大值
单价（元/克）	0.70	1.67	1.78
5 d总费用（元）^a	56.00	133.60	142.13
指标	磷酸奥司他韦颗粒
指标	最小值	基础值	最大值
单价（元/毫克）	0.11	0.27	0.31
5 d总费用（元）^b	49.50	121.50	140.10

组别	最小值	基础值	最大值
对照组	63.6	64.2	64.8
观察组	75.9	76.7	77.5

组别	治疗成本（元）
组别	最小值	基础值	最大值	分布
对照组	49.50	121.50	140.10	Gamma
观察组	56.00	133.60	142.13	Gamma
组别	治疗效果（%）
组别	最小值	基础值	最大值	分布
对照组	63.6	64.2	64.8	Beta
观察组	75.9	76.7	77.5	Beta

Cost-effectiveness analysis of traditional Chinese medicine and western medicine in the treatment of influenza in children

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