儿童肠系膜淋巴结炎的中西医诊治进展

doi:10.20274/j.cnki.issn.1674-3865.2026.02.007

Abstract

Abstract:

Mesenteric lymphadenitis in children is a common pediatric abdominal pain disorder, which has the characteristics of repeated attacks and prolonged course of disease, seriously affecting the physical and mental health and quality of life of children. At present, there is no unified consensus on the diagnostic criteria and treatment of the disease. Anti-infection and symptomatic treatment are still the main clinical treatments, but long-term use of antibiotics can easily cause intestinal flora imbalance and drug resistance. In recent years, the role of probiotics in regulating intestinal microecology, reducing inflammation, shrinking lymph nodes, and assisting the treatment of children with mesenteric lymphadenitis has received increasing attention. The core treatment in traditional Chinese medicine (TCM) is regulating qi and relieving pain, reducing swelling and resolving nodules, and invigorating spleen and stomach, and various interventions are performed, such as oral administration of Chinese medicines, acupoint application, moxibustion and massage, which has achieved great effect. Integrated traditional Chinese and western medicine can synergistically enhance the effect, reduce the recurrence rate and improve the compliance, showing a good application prospect. This article systematically reviews the research progress in etiology, pathogenesis, key diagnostic points, western medicine treatment, traditional Chinese medicine treatment, integrated traditional Chinese and western medicine and probiotics application in children with mesenteric lymphadenitis, and sorts the limitations and controversies of current diagnosis and treatment, so as to provide references for standardized clinical diagnosis and treatment and subsequent researches.

Key words: Mesenteric lymphadenitis, Abdominal pain, Probiotics, Child

CLC Number:

R725.7

Minli GUAN, Xiaolin GAO. Advances in diagnosis and treatment of pediatric mesenteric lymphadenitis based on integrated traditional Chinese and western medicine[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 128-132.

References 43

[1]	李沛琼，孙丽平.脾胃虚寒型小儿肠系膜淋巴结炎经验探析 [J]. 中国中西医结合儿科学，2024, 16 (1): 85-88.
[2]	李小兰,陈宗礼,吴泽湘,等.中医药治疗小儿肠系膜淋巴结炎相关性腹痛的研究进展[J]. 世界科学技术-中医药现代化,2020, 22(1):134-139.
[3]	江载芳,申昆玲,沈颖.诸福棠实用儿科学[M].9版.北京:人民卫生出版社,2022.
[4]	Pavlovic M, Rokvic Z, Berenji K. Efficacy of prednisone in children with acute nonspecific mesenteric lymphadenitis: a pilot study[J]. Acta Medica(Hradec Kralove)， 2022，65(1):25-28.
[5]	黄彩瑜,邵洁贞,陆永钊,等.芍药甘草加味免煎剂联合消旋山莨菪碱片治疗小儿肠系膜淋巴结炎的临床疗效观察[J]. 中医临床研究,2021, 13(16):98-100.
[6]	Dahiya D, Nigam PS. Antibiotic-therapy-induced gut dysbiosis affecting gut microbiota-brain axis and cognition: restoration by intake of probiotics and synbiotics[J]. Int J Mol Sci， 2023，24(4):3074.
[7]	Richard ML, Sokol H. The gut mycobiota: insights into analysis, environmental interactions and role in gastrointestinal diseases[J]. Nat Rev Gastroenterol Hepatol， 2019，16(6):331-345.
[8]	黄群英.益生菌联合复方谷氨酰胺治疗小儿肠系膜淋巴结炎的临床效果探讨[J]. 数理医药学杂志,2020, 33(2):259-260.
[9]	Asadi Amoli A, Mehrabani S, Esmaeili Dooki M,et al. Comparison of clinical findings of acute appendicitis and mesenteric lymphadenitis in children with acute abdominal pain[J]. J Babol Univ Med Sci, 2023,25(1):204-212.
[10]	Cai B, Yi H, Zhang W. Reference intervals of mesenteric lymph node size according to lymphocyte counts in asymptomatic children[J]. PLoS One， 2020，15(2):e0228734.
[11]	姚美美,隆红艳.小儿急性肠系膜淋巴结炎的中医研究进展[J]. 中医临床研究,2023, 15(12):110-114.
[12]	鲁姿岐,姬艺匀,曾肖.桂枝汤加减联合抗生素治疗小儿肠系膜淋巴结炎临床观察[J]. 湖北中医药大学学报,2024, 26(5):25-28.
[13]	朱依,李香君,戴歧康.加味四逆散联合推拿治疗儿童肝脾郁结型肠系膜淋巴结炎临床研究[J]. 新中医,2025, 57(11):54-58.
[14]	郑绍军.思连康联合谓葆在治疗小儿肠系膜淋巴结炎的临床应用[J]. 中国医药科学,2013, 3(13):63-64.
[15]	陈羽,申建国,张亮,等.柴胡桂枝汤加减联合头孢克洛干混悬剂治疗脾胃湿热型小儿肠系膜淋巴结炎临床观察[J]. 河北中医,2020, 42(3):406-409.
[16]	沈丽青,田洪洋,福林. 小儿肠系膜淋巴结炎超声诊断及相关治疗的研究进展[J]. 临床医学进展,2024,14(10):331-337.
[17]	Lahel RS, Chail A. Relevance of mesenteric lymphadenopathy in children detected on sonography[J]. J Mar Med Soc， 2023，25:78-80.
[18]	谢小敏. 不同病原体感染致急性肠系膜淋巴结炎患儿超声图像特征分析[J]. 四川生理科学杂志,2025,47(10):2281-2283.
[19]	包克珍,许云丽.儿童急性肠系膜淋巴结炎122例临床特征分析[J].西南军医,2020,22(5):463-464.
[20]	Kulshrestha V, Tomar P, Kumar S. Clinico-imaging correlation of mesenteric lymphadenitis presented as abdominal pain in children: A tertiary care hospital study in Uttar Pradesh, India[J]. Int J Acad Med Pharm， 2022，4(3):124-129.
[21]	王益畅.修益升治疗肠系膜淋巴结炎的临床观察[J].中国现代药物应用,2020,14(13):208-210.
[22]	丁宗富,王敏,苏仁强,等.针刺配合中药治疗小儿肠系膜淋巴结炎疗效观察[J]. 上海针灸杂志，2016, 35(11):1306-1309.
[23]	莫容如,吴家煜,郭誉丹,等.罗氏三香包联合西药治疗小儿肠系膜淋巴结炎的随机对照研究[J].山东中医杂志,2024,43(12):1407-1413.
[24]	田丽英,冯爽,林婧.双歧杆菌四联活菌联合头孢克肟治疗小儿肠系膜淋巴结炎的临床效果及对消化功能、免疫功能的影响[J]. 临床医学研究与实践,2022, 7(27):118-121.
[25]	张原原,常亚丽,付慧敏.中西医结合治疗小儿肠系膜淋巴结炎疗效观察[J]. 实用中医药杂志,2022, 38(5):797-798.
[26]	张志彪,万齐,黄君,等.盐酸消旋山莨菪碱联合丙帕他莫治疗急性腹痛的临床效果[J].临床合理用药,2023,16(7):56-58.
[27]	陆俊,倪龚柳.理气化痰汤辨证加减联合益生菌治疗小儿急性肠系膜淋巴结炎的疗效分析[J]. 四川中医,2024, 42(4):146-150.
[28]	刘艳凤. 益生菌联合小儿推拿对肠系膜淋巴结炎患儿腹痛程度及对T淋巴细胞亚群水平的影响[J]. 四川生理科学杂志,2024,46(8):1845-1848.
[29]	Pavlovic M, Rokvic Z, Berenji K. Prednisone for the treatment of acute nonspecific mesenteric lymphadenitis[J]. Open Access Maced J Med Sci， 2020，8(C):82-85.
[30]	Zheng Y, Liu Z, Cai A, et al. Study on the mechanism of Ginseng-Gegen for mesenteric lymphadenitis based on network pharmacology[J]. Transl Pediatr， 2022，11(9):1534-1543.
[31]	郭燕燕,袁文静.香砂平胃散联合头孢克肟治疗肠系膜淋巴结炎患儿的效果[J]. 中国民康医学,2025, 37(7):141-143.
[32]	王亚雷,李晨帅.中医药治疗小儿急性肠系膜淋巴结炎的临床研究进展[J]. 基层中医药,2024, 3(8):118-124.
[33]	包小春,李成秀.雷火灸辅治小儿肠系膜淋巴结炎疗效观察[J].实用中医药杂志,2022,38(11):1892-1893.
[34]	黄勋,周海燕,陈黎,等.中药热奄包治疗小儿急性肠系膜淋巴结炎中寒型[J].吉林中医药,2023,43(5):542-545.
[35]	陈敏瑾.中药封包辅助治疗小儿肠系膜淋巴结炎32例临床观察[J]. 中医儿科杂志，2019, 15(3):62-64.
[36]	王倩.止痛散脐周温熨辅治小儿肠系膜淋巴结炎疗效观察[J]. 实用中医药杂志，2020, 36(9):1150-1151.
[37]	陈楚云,戴春丽,梁银婵.自拟腹安散外敷联合大肠俞按压治疗小儿肠系膜淋巴结炎临床护理[J].齐鲁护理杂志,2019,25(7):69-71.
[38]	南丽娟,李莲嘉.桂芍止痛散外敷治疗小儿肠系膜淋巴结炎临床观察[J].光明中医,2021,36(16):2745-2747.
[39]	何秀娇.肠痈消炎汤灌肠治疗胃肠结热型小儿肠系膜淋巴结炎35例[J]. 湖南中医杂志,2022, 38(9):17-20.
[40]	梁桂玲,曾琴,韦府琼,等.中药穴位贴敷联合激光治疗在小儿肠系膜淋巴结炎腹痛中的临床效果[J].妇儿健康导刊,2024,3(8):33-36.
[41]	方吉琴,成莹,吴慧.保和丸联合阿莫西林克拉维酸钾治疗小儿肠系膜淋巴结炎的疗效观察[J]. 中国现代药物应用,2023, 17(22):115-118.
[42]	Liu S, Li J.Research progress of Qiweibaizhu powder in treating digestive system diseases[J].World J Tradit Chin Med,2021,7(4):391-396.
[43]	李晨帅,王亚雷.揿针治疗小儿肠系膜淋巴结炎临床研究[J].光明中医,2024,39(6):1159-1163.

Advances in diagnosis and treatment of pediatric mesenteric lymphadenitis based on integrated traditional Chinese and western medicine

RichHTML

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References 43

Related Articles 15

Recommended Articles

Metrics

Comments

[1]	Lizheng JIN, Jiapei LIN, Hanyu SUN, Guangju HUANG. Research progress on influencing factors for childhood asthma control [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 104-110.
[2]	Qing YANG, Jingnan XUE, Liujin JIA. Experience of Professor Jia Liujin in treating pediatric pneumonia with dyspnea and cough [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 111-115.
[3]	Zhe ZHOU, Huina LU, Ming ZHANG, Ling DONG. Research on the clinical experience of Professor Xu Rongqian in treating children with cough variant asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 116-121.
[4]	Xuting WANG, Peng ZHOU. Research status of specific immunotherapy for childhood asthma [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 122-127.
[5]	Lei XU, Shi ZHANG, Jiujun QIU, Wenjing ZHANG, Shaomin LIANG, Lin HOU, Hong WANG. Common misconceptions and treatment strategies in occupational therapy for children with cerebral palsy [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 133-136.
[6]	Shihui TANG, Xuefeng WANG, Kexin ZHANG. Professor Wang Xuefeng's exploration in the clinical experience in pediatric pneumonia with dyspnea and cough based on the theory of "What is within manifests without" [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 137-140.
[7]	Meifang CHEN, Jian ZHENG. Professor Zheng Jian's experience in treating refractory nephrotic syndrome in children based on the principle of "phased collaboration and sequential synergy" [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 141-146.
[8]	Hang YANG, Mingzhang LI, Xi LI, Xinchen WU, Xiangjuan SUN. Application of the "aromatic orifice-opening" method in pediatric pulmonary and nasal diseases [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 147-151.
[9]	Yuhan WU, Dan YUAN, Xinxin HUANG, Yinglong CHEN, Yingying KE, Qian LIN, Shiyi ZENG. Exploration of Professor Yuan Dan's experience in treating infantile enuresis from the perspective of blood stasis [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 152-156.
[10]	Baoyi HUANG, Lichen YI, Yabin CHEN, Hua XU. Exploring Professor Xu Hua's experience in treating pediatric patients post-hematopoietic stem cell trans⁃plantation based on data mining [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 157-167.
[11]	Xuejiao WANG, Chen SHEN, Miao YU, Yiwen GAO, Heng LI. Clinical efficacy analysis of foot bath with Jiebiao Toure decoction combined with meridian scraping in the treatment of exogenous fever (wind-heat type) in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 168-173.
[12]	Yingying WU, Jinming LI, Caixiao SHI, Qing SHANG, Xiangli WANG, Liang HAN. Observation on the efficacy of pelvic floor magnetic stimulation combined with bladder function training in children with neurogenic bladder after spinal cord injury [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 174-179.
[13]	Enhui ZHANG, Linlin WANG, Bo LIU. Analysis of differences in vitamin A, D and E levels in preschool children with allergic diseases and their correlation with risk of severe pneumonia [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 180-184.
[14]	Guining LU, Shunhuan MAI, Xiaojin OUYANG, Guochun HUANG, Yajun WANG, Yuejian ZHANG, Tingting PAN. Study on the application effect of standardized medical record system combined with Internet-based management model in childhood asthma control [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 93-97.
[15]	Jiongnan WEN, Yuansha WANG, Mengyi XU, Yi LÜ, Haixia LI. Exploring the mechanism of action of Buzhong Yiqi decoction in the treatment of pediatric combined allergic rhinitis and asthma syndrome based on network pharmacology and molecular docking technology [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(2): 98-103.