静灵口服液治疗儿童抽动障碍临床观察

doi:10.20274/j.cnki.issn.1674-3865.2026.04.013

Abstract

Abstract:

Objective To investigate the clinical efficacy of Jingling oral solution in the treatment of transient tic disorders in children. Methods A total of 60 children with tic disorders treated in the Pediatric Outpatient Department of Shandong Provincial Maternal and Child Health Care Hospital from September 2022 to September 2024 were enrolled as research subjects and randomly divided into an observation group and a control group, with 30 cases in each group. The observation group was treated with Jingling oral solution, while the control group received tiapride hydrochloride. Both groups were treated for one course of treatment (3 months). The clinical efficacy was evaluated using the Yale Global Tic Severity Scale (YGTSS) and standardized traditional Chinese medicine (TCM) syndrome scoring scale, and the safety of the medications was assessed. Results There was no statistically significant difference in the total effective rate between the two groups after treatment (P>0.05). The YGTSS scores of both groups after treatment were significantly lower than those before treatment, with statistically significant differences (P<0.05); there was no statistically significant intergroup difference in YGTSS scores before or after treatment (P>0.05). The TCM syndrome scores of both groups decreased after treatment, and the scores of the observation group were lower than those of the control group, with statistically significant differences (P<0.05). No obvious adverse reactions were observed in the observation group after treatment, whereas mild adverse reactions occurred in the control group. Conclusion Jingling oral solution can effectively alleviate tic symptoms and TCM syndromes in children with transient tic disorders of Yin?deficiency and wind?stirring syndrome, with favorable medication safety.

Key words: Transient tic disorders, Jingling oral solution, Clinical observation, Child

CLC Number:

R748

Min KONG, Hui LI, Yuena GAO, Feng ZHANG. Clinical observation on the treatment for tic disorders in children by Jingling oral solution[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2026, 18(4): 340-343.

Figures/Tables 3

References 30

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组别	n	临床控制	显效	有效	无效	总有效
对照组	30	4（13.3）	11（36.7）	10（33.3）	5（16.7）	25（83.3）
观察组	30	3（10.0）	10（33.3）	11（36.7）	6（20.0）	24（80.0）

组别	n	治疗前	治疗后	t值	P值
对照组	30	16.02±3.13	5.83±2.35	19.78	<0.001
观察组	30	15.97±3.06	5.67±2.09	20.83	<0.001
t值		0.06	0.28
P值		0.951	0.784

组别	n	治疗前	治疗后	t值	P值
对照组	30	3.29±0.60	2.27±0.56	7.42	<0.001
观察组	30	3.17±0.58	1.21±0.47	13.04	<0.001
t值		0.79	7.52
P值		0.433	<0.001

Clinical observation on the treatment for tic disorders in children by Jingling oral solution

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