防哮颗粒对哮喘缓解期模型大鼠气道炎性损伤的预防作用

doi:10.3969/j.issn.1674-3865.2010.01.021

Abstract

Abstract: ObjectiveTo discuss the mechanism of antiasthma particles on preventing inflammatory airway damage in asthma remission stage.
MethodsProduce rat model of asthma in remission stage to observe the impact of the antiasthma particles concentrate on the serum IL4,EOS,and IgE of the model after gastric perfusion.Compare it with Guben Kechuan Tablets and ketotifen positive controlled groups.
ResultsAntiasthma particles could reduce levels of serum EOS,inflammatory cytokines IL4 and immune factors IgE in model rats with asthma in remission stage，and had statistically meaning compared with the positive controlled groups（P<0.05）.
ConclusionsAntiasthma particles can inhibit airway inflammation and reduce airway hyperresponsiveness in the model rats,so it has good preventive effect on inflammatory airway damage in model rats with asthma in remission stage.

Key words: Antiasthma particles/therapeutic, Asthma, IL；EOS, IgE；Rat

Xing Xianghui，Chen Lu，Song HuiXiao.. The preventive effect of antiasthma particles on inflammatory airway damage of model rats with asthma in remission stage[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2010, 2(1): 49-51.

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The preventive effect of antiasthma particles on inflammatory airway damage of model rats with asthma in remission stage

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