Abstract:
Objective：To analyze the clinical features and the examination results of nerve conduction in hand-foot-mouth disease（HFMD） combined with acute flaccid paralysis（AFP）which may be helpful in clinical diagnosis,treatment and the prognosis judgement.
Methods：Five cases of HFMD combined with AFP who made regular followup visits to our hospital from June 2012 to June 2014 were selected. The clinical features and followup data of nerve conduction were analyzed retrospectively.
Results：Axonal or anterior horn cells injury was the main type in this disease. There was a positive correlation between the decrease of action potential amplitude and limb dysfunction. The return of action potential amplitude was most prominent in the first review.The femoral nerve injury was the most common. The decrease of action potential amplitude of motor conduction was seen. The cases whose amplitude decreased 30% and below during the early onset could be observed limb dysfunction after 6～12 months.
Conclusion：In the management of HFMDcombined with AFP,it is important to diagnose and treat in time to reduce the rate of disability.

Key words: Hand-foot-mouth disease(HFMD), complication, Acute flaccid paralysis(AFP), complication, Nerve conduction, Diagnosis, Children