ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2015, Vol. 7 ›› Issue (6): 584-586.doi: 10.3969/j.issn.1674-3865.2015.06.017

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Observation on the clinical efficacy of Xiaoer Chiqiao Qingre granule for herpangina in children

ZHANG Hua   

  1. Zhumadian City First People's Hospital, Henan 463000,China.
  • Online:2015-12-25 Published:2018-11-19

Abstract:
Objective:To observe the clinical curative effect and drug safety of Xiaoer Chiqiao Qingre granule in the treatment of child herpangina.
Methods:A total of 156 cases of herpangina were randomly divided into control group and observation group, with 78 cases in each group. The control group was given conventional treatment of ribavirin antiviral therapy, while the observation group was given Xiaoer Chiqiao Qingre granule on the basis of ribavirin antiviral treatment;observe the clinical efficacy and drug safety of the two schemes.
Results:The total effective rate of observation group was 96.2%(75/78), which was significantly higher than the 84.6% of control group(66/78), the difference being statistically significant (P<0.05).The time for appetite to return to normal had no statistically significant difference between the two groups(P>0.05). The incidence of drug reactions was 3.8%(3/78) in the control group, and compared with the 5.1%(4/78) of observation group, there was no statistically significant difference(P>0.05).
Conclusion:The scheme of combining Xiaoer Chiqiao Qingre granules with the conventional antiviral treatment to treat child herpangina has quick and significant effect, and its drug safety is not lower than conventional antiviral drugs.

Key words: Herpangina, Xiaoer Chiqiao Qingre granule, therapeutic use, Drug safety, Children