ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2016, Vol. 8 ›› Issue (1): 15-18.doi: 10.3969/j.issn.1674-3865.2016.01.006

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Clinical features of severe mycoplasma pneumoniae pneumonia in 39 children and analysis of curative effect of glucocorticoids

YIN Xiaobo,WU Xiuqing,SHI YIfang,MAO Zhiqin,MU Yaping   

  1. Shenyang Children's Hospital,Shenyang 110032,China
  • Online:2016-02-25 Published:2018-11-19

Abstract:
Objective:To analyze the clinical features of severe mycoplasma pneumoniae pneumonia(MPP) and observe the curative effect of glucocorticoids.
Methods:A total of 39 children hospitalized for severe mycoplasma pneumoniae pneumonia from July 2013 to December 2013 were divided into glucocorticoid group and control group.Compare the time of fever relief and spasmatic cough and hospital stay between the two groups.
Results:All the 39 cases of children had the symptom of fever and spasmatic cough,which lasted for 5 to 10 days.There were 29 cases whose white blood cell increased.Large piece of shadow or pulmonary infiltrates shadows were found in imaging examination,including 5 cases in both sides of lung and 34 cases in one side.All serum MP-IgM was equal to or more than 160.Eight cases had pleural effusion,2 cases had pulmonary atelectasis,and 6 cases had abnormal liver function.Myocardial enzyme spectrum was abnormal in 5 cases,and erythra was found in 2 cases.The time of fever and spasmatic cough of the glucocorticoid group was (6.7±1.3)d and (5.35±1.62)d, less than (8.3±1.4)d and (7.27±1.58)d of the control group(P<0.05).The length of hospital stay of glucocorticoid group and control group was (14.8±6.2)d and(12.8±3.3)d(P>0.05),respectively,and there was no difference between the two groups.
Conclusion:Severe mycoplasma pneumoniae pneumonia of children can lead to severe intrapulmonary infection and a variety of extrapulmonary complications.Early use the glucocorticoids can result in good effect.

Key words: Pneumonia, mycoplasma, Glucocorticoid/therapeutic use, Children