ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2016, Vol. 8 ›› Issue (1): 91-93.doi: 10.3969/j.issn.1674-3865.2016.01.033

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Effect of Xiaoer Chaigui Tuire granule combined with ribavirin on the immunity of children with acute upper respiratory tract infection

LU Yanhong   

  1. Department of Pediatrics,Guangxi Laibin People's Hospital,Laibin 546100,China.
  • Published:2016-02-25 Online:2018-11-19

Abstract: Objective:To investigate the effect of Xiaoer Chaigui Tuire granule combined with ribavirin on the immunity of children with acute upper respiratory tract infection.
Methods:A total of 216 cases of acute upper respiratory tract infection in children admitted to Laibin People's Hospital from Jan. 2014 to June 2015 were randomly divided into three groups:control group Ⅰ(62 cases) treated with Xiaoer Chaigui Tuire granule,control group Ⅱ(68 cases) given ribavirin for injection,and the observation group(86 cases) receiving treatment of Xiaoer Chaigui Tuire granule combined with ribavirin;another 30 normal children were chosen during the same period as the normal control group.Compare and analyze the changes of immunity in the children of each group before and after the treatment.
Results:Before treatment,CD3+,CD4+,and CD4/CD8 were remarkably lower in observation group and control group Ⅰ and Ⅱ than in normal control group,while CD8+ was higher,the difference being of statistical significance(P<0.05);the improvement of CD3+,CD4+,CD8+,and CD4/CD8 in observation group was better than in control group Ⅰ and Ⅱ,and the difference being statistically significant(P<0.05);the total effective rate in observation group was 97.7%(84/86),remarkably higher than control group Ⅰ(83.9%,52/62),the difference being statistical significant(P<0.017);Pearson linear correlation analysis showed that the clinical effect in child patients was positively related to the immunity indexes of CD3+,CD4+,CD8+ and CD4/CD8.
ConclusionThe treatment with Xiaoer Chaigui Tuire granule combined with ribavirin for acute upper respiratory tract infection is probably through enhancing the immune function of human body.

Key words: Acute upper respiratory tract infection, Xiaoer Chaigui Tuire granule/treatment application, Ribavirin/treatment application, Children