Abstract:
Objective: To investigate the clinical effect of mucosolvan given in different ways in the treatment of neonatal pneumonia.
Methods: Totally 86 cases of neonatal pneumonia were selected in the Pediatric Department of People′s Hospital of Ruyang County from Aug.2012 to Oct.2014,and according to the different treatment options they were divided into control group and observation group,43 cases in each group.The control group was given constant temperature incubator,oxygen,anti-infection,correction of acid-base imbalance,energy mixture of nutritional support and other conventional symptomatic treatment.At the same time,intravenous infusion of mucosolvan treatment was given.The observation group was given mucosolvan inhalation therapy in addition to the above treatment.The treatment time,clinical efficacy and adverse drug reactions were observed and compared between the two groups.
Results: There was no significant difference in the total effective rate between the two groups(P>0.05).The cure rate of observation group was 95.4%(41/43),significantly higher than that of the control group［79.1%(34/43)］,the difference being statistically significant(P<0.05).In the observation group,treatment time was(7.4±2.1)d,significantly shorter than the control group(10.4±2.9)d,the difference being statistically significant (P<0.05).Adverse drug reactions were mild in the two groups during the treatment period,the difference being not statistically significant(P>0.05).
Conclusion: Mucosolvan aerosol inhalation combined with intravenous use can control clinical symptoms quickly,shorten the treatment time and improve the cure rate.It is safer and has no obvious adverse drug reactions.

Key words: Pneumonia, Mucosolvan, Intravenous infusion, Atomizing inhalation, Infant,newborn