Objective:To observe the curative effect of Pingfu powder (No.1 and No.2) in the treatment of children with mesenteric lymphadenitis.

Methods:A total of 106 children visiting the outpatient department were randomly divided into two groups: observation group and control group,53 children in each group. For the observation group, Pingfu powder(No.1 and No.2) was taken orally respectively according to the different clinical syndrome. For control group, azithromycin suspension was given, and acyclovir sustained release tablets were also given. The treatment lasted 7 days for both groups as a course.

Results：The cure rate was 77.36%(41/53) for observation group and 50.94%(27/53) for control group, and there was statistical difference(P＜0.05). Some children had more times of bowel movement after taking Pingfu powder(No.2) for several days in the observation group, but returned to normal after the treatment course. Some children in control group had skin rash and gastrointestinal symptoms.

Conclusion：Pingfu powder has significant effect in the treatment of children with acute mesenteric lymphadenitis, and it has no obvious adverse reactions, so it should be clinically promoted and used.