丙种球蛋白联合糖皮质激素治疗儿童特发性血小板减少性紫癜疗效观察

doi:10.3969/j.issn.1674-3865.2016.06.015

Abstract

Abstract: Objective:To observe the curative effect of gamma globulin combined with glucocorticoid in the treatment of children with idiopathic thrombocytopenic purpura.
Methods:A total of 80 children with ITP who were hospitalized for treatment in Hunan Children's Hospital from Jan. 2015 to may 2016 were randomly divided into two groups: observation group(40 children) and control group(40 children). The control group was given glucocorticoid for treatment, and the observation group was given Gramma globulin in addition to glucocorticoid. The treatment course lasted 21 to 28 days. Observe the curative effect in the two groups; the time of platelet count to increase and to return normal was also recorded.
Results:The total effective rate in observation group was 95.0%(38/40), significantly higher than that of control group(77.5%,31/40), and the difference was statistical(P<0.05). The time of platelet count to increase and to return to normal in observation group was shorter than that in control group, and there was statistical difference(P<0.05).
Conclusion：Gamma globulin combined with glucocorticoid achieves significant effect in the treatment of ITP children.

Key words: Idiopathic thrombocytopenic purpura, Gamma globulin, Glucocorticoid, Children

YANG Haixia. Gamma globulin combined with glucocorticoid in the treatment of children with idiopathic purpura: an observation on the effect[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2016, 8(6): 597-599.

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Gamma globulin combined with glucocorticoid in the treatment of children with idiopathic purpura: an observation on the effect

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