Abstract: Objective:Through detecting and analyzing the serum allergen in children with allergic diseases and suspected allergic diseases in Liaoyang area, to provide evidence for the prevention and treatment of allergic diseases.
Methods:A total of 2 641 children with allergic diseases and suspected allergic diseases were screened by western blotting, and clinical data were analysed retrospectively.
Results:Totally 737(28.19%) out of 2 641 children were with positive allergens, 1 717 cases were 0-3-year old, and 394(22.95%) of them were positive for allergen screening; in 897 cases of 3-14-year old children， 343 cases(38.24%) were positive for allergen screening. Inhalant allergens were as follows(from high to low): house dust mites, mixed mold, dog hair dander, cat hair dander, house dust, mixed grass pollen(Artemisia/short ragweed/Humulus/amaranth), mixed tree pollen(cypress/elm/willow/birch/maple/walnut/sycamore/poplar)，and cockroaches； food allergens were as follows(from high to low): milk, eggs, crab, cashew nuts/peanuts/soy, shellfish/fish, shrimp, beef/lamb, mango/apple/cherry/peach;0-3-year old children were commonly allergic to milk, eggs and other food allergens , and 3-14-year old children were commonly allergic to house dust mites, mold and other mixed inhalant allergens.
Conclusion：Milk, eggs and other food allergens are major allergens of allergic diseases in 0-3-year old children, with the age growing, food allergens gradually decreased, while house dust mites, mixed mold and other inhaled allergens become the main allergen.

Key words: Allergic disease, Allergen, Specific IgE, Children