雾化吸入普米克令舒联合可必特治疗对哮喘患儿免疫功能的影响

doi:10.3969/j.issn.1674-3865.2017.03.011

Abstract

Abstract:
Objective
To investigate the effect of aerosol inhalation of pulmicort respules combined with Combivent on immune function in children with asthma.
Methods
A total of 120 children with mild to moderate asthmatic diseases treated in Supplementary Department of Shaoguan First People's Hospital from January 2015 to March 2016 were selecetd, and they were divided into observation group and control group by random number table, 60 cases in each group. Control group was given aerosol inhalation of pulmicort respules, while observation group was treated with aerosol inhalation of pulmicort respules combined with Combivent. After a twoweek treatment, the clinical efficacy, remission time of clinical signs, lung function［peak expiratory flow(PEF), PEF%］ and immunological indexes ［immunoglobulin E(IgE) and eosinophil(EOS)］ were compared between the two groups.
Results
The total effective rate of observation group was 96.67%(58/60), which was higher than 81.67%(49/60) of control group(P<0.05). The disappearance time of cough, asthma, wheezing rale in observation group were shorter than those in control group(P<0.05). After treatment, the levels of PEF and PEF% in two groups significantly increased, and observation group was higher than control group(P<0.05). After treatment, the levels of IgE and EOS in two groups significantly decreased, and observation group was lower than control group(P<0.05).
Conclusion
Aerosol inhalation of pulmicort respules combined with Combivent is effective in treatment of children with asthma, and it can accelerate recovery and improve lung function and immune function, which is worthy of wide clinical application.

Key words: Asthma, Aerosol inhalation, Pulmicort respules, Combivent, Immune function, Children

LAI Huaji, LIN Shijiang, LI Yonghua, HE Gaofeng, RAO Huiling. Effect of aerosol inhalation of pulmicort respules combined with Combivent on immune function in children with asthma[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2017, 9(3): 219-221.

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Effect of aerosol inhalation of pulmicort respules combined with Combivent on immune function in children with asthma

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