ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2017, Vol. 9 ›› Issue (5): 407-409.doi: 10.3969/j.issn.1674-3865.2017.05.013

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Observation of the curative effect of Nephritis Rehabilitation tablet on hematuria and albuminuria in children with Henoch Schonlein purpura nephritis

DING Yunfeng,LI Zhihui,DUAN Cuirong,XUN Li,WU Tianhui,ZHANG Yi   

  1. Hunan Children's Hospital, Changsha 410007,China
  • Online:2017-10-25 Published:2017-12-18

Abstract:
Objective
To observe the efficacy and safety of Nephritis Rehabilitation tablets in treatment of hematuria and proteinuria in children with Henoch Schonlein purpura nephritis.
Methods
From November 2015 to December 2016, 112 children with Henoch Schonlein purpura nephritis complicated with hematuria and proteinuria were treated in Hunan Children's Hospital, and they were randomly divided into Both groups and the observation group, each with 56 cases. Both groups were given anti-allergy and symptomatic treatment. The observation group was also treated with Nephritis Rehabilitation tablets, 2 weeks as 1 course, and all patients received the treatment for 3 courses. The efficacy and safety of the two groups were compared.
Results
The total effective rate of observation group was 78.5%(44/56),higher than that of the control group(60.7%,34/56)(P<0.05); in observation group incidence rate of adverse reaction was 19.64%(11/56), significantly lower than the control group(73.21%,41/56)(P<0.05).
Conclusion
For children with purpura nephritis accompanied by hematuria and proteinuria, the treatment of Nephritis Rehabilitation tablets has significant effect, and it is safe with no obvious toxic and side effects.

Key words: Henoch Schonlein purpura nephritis, Nephritis Rehabilitation tablet, Hematuria, Proteinuria, Safety, Children