Abstract:
objective
To explore the relationship between tic disorder and food intolerance in children.
Methods
Children with tic disorder were chosen，who were treated in the Department of Pediatric Care Clinic and Allergy Clinic, Dalian Children's Hospital Affiliated to Dalian Medical University from April 1st 2015 to January 31st 2017 and with foodspecific IgG positive by ELISA testing. The patients were divided into two groups：intervention group and no-intervention group. All patients were followed up for 1 month, 3 months and 6 months to evaluate the effective rate of alleviating tic symptoms.
Results
Toally 32 cases of TD children received food intolerance test, including 24 boys and 8 girls. The average age was （6.66±2.46）years, ranging from 3 to 11 years. Of these patients, 30 cases appeared positive with positive rate being 93.4%. The positive rate of one kind of food specific IgG was 13.3%(4 cases), two kinds 53.3%(16 cases), three kinds 6.7%(2 cases), and four kinds 26.7%(8 cases). The food with highest increase of food-specific IgG was egg(87.5%), followed by milk(53.1%), flour(43.4%), tomato(25%), fish(18.8%), soybean(15.6%), corn(12.5%),rice(12.5%), crab(9.4%), shrimp(6.3%), chicken(6.3%), pork(3.1%)，beef(3.1%) and mushrooms(0). For nointervention group, the remission rate of tic symptoms in the 3 times of followup was 20%(4/20), 30%(6/20) and 40%(8/20) respectively, while the remission rate of tic symptoms was 30%(3/10), 50%(5/10) and 80%(8/10), respectively in the intervention group.
Conclusion
Most TD children also have food intolerance. The most common foods are egg, milk, flour and tomato. After dietary intervention, the tic disorder children with food intolerance-positive show a gradual alleviating trend with the time passing.

Key words: Tic disorders, Food intolerance, Children