ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2018, Vol. 10 ›› Issue (2): 127-129.doi: 10.3969/j.issn.1674-3865.2018.02.011

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Observation of curative effect of Lianhua Qingwen granule on children with infectious mononucleosis

HU Wenmiao   

  1. Paediatric Department of the Third People's Hospital of Zhengzhou, Zhengzhou 450000, China
  • Online:2018-04-25 Published:2018-11-19

Abstract:
objective
To observe the clinical effect of Lianhua Qingwen granule combined with ganciclovir in the treatment of infectious mononucleosis in children.
Methods
A total of 62 cases of infectious mononucleosis who were treated in the Third People's Hospital of Zhengzhou from March 2012 to March 2017 were selected and divided into two groups: 32 cases in the observation group and 30 cases in the control group. The observation group was treated with Lianhua Qingwen granule combined with ganciclovir, while the control group was given ganciclovir only, the course of treatment being 7 to 14 days. The clinical efficacy and relief time of clinical symptoms and signs in the two groups were observed and compared.
Results
The total effective rate in the observation group was 90.7%(29/32), which was significantly higher than that in the control group(70.0%,21/30), the difference being statistically significant(P<0.05). The time of the temperature returning to normal, the remission time of angina and the swelling of the neck lymph node and the retraction time of liver and spleen were significantly shorter in observation group than those in the control group, the difference being statistically significant(P<0.05).
Conclusion
Lianhua Qingwen granule combined with ganciclovir in the treatment of IM can significantly shorten the fever time and rapidly improve the clinical symptoms and the curative effect.

Key words: Infectious mononucleosis, Lianhua Qingwen granule, Ganciclovir, Children