Abstract:
Objective
To evaluate the clinical efficacy and safety of Shang Shi Fang and Yi Qi Yang Yin Fang in preventing recurrent respiratory tract infection(RRTI) in children.
Methods
From July 2015 to July 2016, 90 children with RRTI were treated in the Outpatient Department of Xiamen Hospital of Traditional Chinese Medicine(gastrointestinal heating or Qi-Yin-deficiency syndrome),who  were randomly divided into observation group(n=45) and control group(n=45). According to the physical constitution of the children, the observation group was given timely treatment with Shang Shi Fang and Yi Qi Yang Yin Fang, with continuous intervention for 1 year and follow-up for 1 year, while the control group was not intervened. The types, frequency, course and curative effect of respiratory tract infection were observed before and after treatment.
Results
After treatment, both groups got improved in the frequency, course and types of disease, and the observation group was significantly superior to the control group, with statistically significant differences(P<0.05). After 12 months of follow-up, the observation group was significantly better than the control group in the reduction of frequency of upper respiratory tract infection and tracheitis(P<0.05). The incidence of pneumonia decreased in both groups after treatment, but the difference was not statistically significant(P>0.05). The effect of the observation group was better than that of the control group, and the difference was statistically significant(P<0.05). No adverse events or adverse reactions were reported in both groups.
ConclusionIt can reduce the incidence of recurrent respiratory tract infection in children to use Shang Shi Fang and Yi Qi Yang Yin Fang at a proper time.

Key words: Recurrent respiratory tract infections, Constitution, Preventive treatment of disease, Child