槐杞黄颗粒对呼吸道合胞病毒毛细支气管炎患儿的治疗效果及免疫调节作用研究

doi:10.3969/j.issn.1674-3865.2018.06.008

Abstract

Abstract:
Objective
To explore the effect of Huaiqihuang granule on children with respiratory syncytial virus(RSV) bronchiolitis and its immunomodulatory effect.
Methods
Ninety cases of RSV bronchiolitis were treated in our hospital from July 2016 to June 2017, and they were randomly divided into the control group and the observation group，45 children in each group. The control group was treated with routine treatment，The observation group was treated with Huaiqihuang granule on the basis of the treatment for control group,6 months as 1 course. The curative effect and immunological indexes(IgA,IgG,IgM,IgE and IL-17 and IL-23) of the two groups were compared.
Results
The total effective rate of the observation group（93.33%,42/45） was significantly higher than that the control group(73.33%,33/45)(P<0.05).The time of clinical symptoms disappearing, antipyretic time and length of hospitalization in the observation group were significantly shorter than those of the control group(P<0.05).The level of IgA, IgG and IgM in the observation group was significantly higher than that of the control group, while the levels of IgE, IL-17 and IL-23 were significantly lower(P<0.05).
ConclusionHuaiqihuang granule has significant effect on children with respiratory syncytial virus bronchiolitis. Immune regulation can be enhanced.

Key words: Bronchiolitis, Respiratory syncytial virus, Huaiqihuang granules, Immunomodulatory, Child

DU Guiqin. Effect of Huaiqihuang granule on children with respiratory syncytial virus bronchiolitis and its immunomodulatory effect[J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2018, 10(6): 484-486.

[1]	. Expert consensus in integrated traditional Chinese and western medicine prevention and treatment for influenza in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 369-.
[2]	NIU Zhenbing, LIU Jing, FENG Lili. Value of the combination detection of β2-microglobulin and neutrophil gelatinase-associated lipocalin in early renal injury in children with infectious mononucleosis [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 399-.
[3]	LUO Lan, LIU Pingping, FANG Sisi. Study on resting energy expenditure of children with sepsis at acute stage [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 405-.
[4]	TANG Xiaoli, DENG Hongbo. Retrospective analysis of the clinical characteristics of 23 children with pertussis [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 416-.
[5]	XU Sha. Effect of pidotimod combined with vitamin AD on children with recurrent respiratory tract infection [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 421-.
[6]	XIE Ying. Retrospective investigation of risk factors in hospitalized children with recurrent respiratory tract infection [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 425-.
[7]	ZHANG Junqing, GUO Liang, SHI Cannan, WANG Jun. Changes and prediction analysis of the mortality of infants and children under 5 years old in Henan Province [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 428-.
[8]	DU Linlin, WANG Yonghong, HE Jingwei. Study on the medication rules for cough in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 431-.
[9]	DU Fuli, DAI Xiaoyu, ZHENG Yapei, ZHENG Hong. Discussion on the treatment of children's short stature based on time medicine of traditional Chinese medicine [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(5): 454-.
[10]	WANG Shengnan, WANG Guojie, WANG Hai. Observation on the effect of Weijing Ditan decoction in the treatment of children with protracted bacterial bronchitis [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(4): 281-.
[11]	HAN Jing, XU Yan, SUN Liping. Research progress in clinical application of Huaiqihuang granules in pediatrics [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(4): 292-.
[12]	WANG Shiyan, MA Bingxiang, LI Ruixing, XU Pingping. Research progress of tic disorder in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(4): 297-.
[13]	YUAN Jianzai, ZHANG Li, YUAN Yehong, MA Shuxia. Advances in research on the treatment for upper airway cough syndrome based on TCM syndrome differentiation [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(4): 301-.
[14]	LI Yi, SHEN Zhaobo, HUA Li. Observation on the efficacy of dust mite drops combined with terbutaline and montelukast in the treatment of allergic asthma in children [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(4): 325-.
[15]	LI Peng. Different doses of dexmedetomidineby nasal dripping in surgery for pediatric hernia [J]. Chinese Pediatrics of Integrated Traditional and Western Medicine, 2021, 13(4): 328-.

Effect of Huaiqihuang granule on children with respiratory syncytial virus bronchiolitis and its immunomodulatory effect

PDF (PC)

Knowledge

Abstract

Cite this article

share this article

References

Related Articles 15

Recommended Articles

Metrics

Comments