Abstract:
ObjectiveTo assess the effect and safety of kidneynourishing herbs for internal use in treatment of enurisis in children, so that clinical treatment decision can be made based on objective believable evaluation of the treatment.MethodsAll the articles about RCT of the kidneynourishing herbs for internal use for enurisis in children were searched for based on the method of evidencebased medicine.The articles that met the inclusion criteria were evaluated by the quality and Jadad scale.Then the data were collected and analysed by Revman 4.2 software.The data were described if they could not be metaanalyzed.So we assessed the efficiency of the internal used herbs for the treatment of enuresis in children.ResultsEight RCTs were included in this review from sixty literatures on controlled studies.The quality of the included studies is seven in C class, one in B class.Jadad scores of 2 points is in one, 4 points in one and 1 in six.Meta analyses showed:the cure rate of the treatment of internal herbs combined with behavior therapy was higher than that of the western medicine.But the upturn rate had no difference.The internal used herbs had no significent differences in the cure rate and upturn rate compared with the western medicine.The treatment of unlimited therapy and period had similar result to that of the internal used herbs.ConclusionsThe effects of the herbs nourishing the kidney for singly internal use are not affirmative.But the cure rate is higher than the western medicine when the herbs are combined with the behavior therapy.The qualities of the included studies are Clevel or Blevel evidence.It needs to be further assessed by highquality, largesample and multicenter RCTs.

Key words: traditional Chinese medicine therapy, treatment application/kidneynourishing herbs, enurisis, children, systematic evaluation