ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2013, Vol. 5 ›› Issue (5): 387-389.doi: 10.3969/j.issn.16743865.2013.05.002

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Experimental study on antitussive expectorant and antiasthmatic effects of Zhixiao Pingchuan granule in animal models Peng Zhengping,Ji Xiaohua,Den Yunlong,et al. Xiyuan Hospital,China Academy of Chinese Medical Sciences,Beijing 100091,China

  

  • Online:2013-10-25 Published:2019-06-18

Abstract:
ObjectiveTo investigate the antitussive,expectorant and antiasmatic effects of  Zhixiao Pingchuan granule(ZXPC) on animal models.
MethodsThe ammonia induced cough model in mice,phenol red secreting tests in mice and asthma induced by spraying method in guinea pig were adopted for observing the ZXPC effects of antitussion,expectorant and antiasthma.
ResultsZXPC can distinctly protract delitescence and increase musculus tracheal phenol red secretion.ZXPC could effectively proevent guinea pigs from asthma induced by histamine and acteylcholine mixture.
ConclusionZXPC has significant antitussive,expectorant and antiasmatic effects on animal models.

Key words: asthma;cough/therapy;Zhixiao Pingchuan granule/therapeutic use, phlegm, asthma, animal experimental