Abstract:

Objective
To investigate the efficacy and safety of Mucopolysaccharide polysulfate cream combined with Desonide cream in the treatment of infantile eczema.
Methods
From September 2017 to March 2018, 200 cases of infantile eczema were treated in the dermatology clinic of Shengjing Hospital Affiliated to China Medical University. They were randomly divided into a control group and an observation group, each with 100 cases. The observation group was treated with Desonide cream and Mucopolysaccharide polysulfate cream for external use; the control group was treated with topical Desonide cream alone. The rash and adverse reactions were recorded at the first week, the second week, and the fourth week of treatment.
Results
After two weeks of treatment, the total effective rate of the observation group was 88.0%(88/100), which was significantly higher than that of the control group, 77.0%(77/100), the difference being statistically significant(P<0.05). After four weeks of treatment, the recurrence rate of the observation group was 16.0%(16/100), which was significantly lower than that of the control group(48.0%,48/100), and the difference was statistically significant(P<0.05). No adverse reactions were found during the treatment in both groups of children.
ConclusionMucopolysaccharide polysulfate cream combined with Desonide cream is effective in treating infantile eczema, with lower recurrence rate and fewer adverse reactions, and is relatively safe. It is worthy of promotion in clinical practice.

Key words: Eczema, Mucopolysaccharide polysulfate cream, Desonide cream, Infant