Abstract: Objective:To investigate the clinical features of infantile persistent bacterial bronchitis.Methods:Totally 126 cases were selected and treated with antibiotics in the Department of Pediatrics in People′s Hospital of Ruyang County from February 2010 to March 2015,and the clinical characteristics and treatment effect were analyzed.Results:The main clinical manifestations were persistent cough,and roles could be heard;among the 126 cases,91 cases (72 2%) were accompanied by wheezing;it was not regular during day and night;the mean time of cough was (4 7±0 3) weeks.Edema and congestion of tracheal mucosa were observed under the microscope,and 48 cases(38 1%) were with airway softening.Laboratory tests showed that the proportion of CD3-CD16+ increased.The positive rate of bacterial culture in bronchoalveolar lavage fluid was 365% (46/126).The main pathogens were Haemophilus influenzae and Streptococcus pneumonia,and neutrophil elevation was 70 6%(89/126).The patients had good prognosis after treatment with the third generation cephalosporin or amoxicillin clavulanate,the average treatment time (15 4±3 6)d.Conclusion:The main clinical features of infantile persistent bacterial bronchitis are persistent cough with moist rales,and some children have wheezing symptoms,which can be accompanied by airway softening.The main pathogens are Haemophilus influenzae and Streptococcus pneumoniae.Positive antibiotic treatment can produce better therapeutic effect.

Key words: Bacterial bronchitis, Clinical features, Treatment, Children