Objective：To observe the clinical effect of Simotang oral liquid and Bifico on pediatric functional dyspepsia.

Methods：According to the random number table, 114 cases of pediatric functional dyspepsia were randomly divided into the control group and the observation group, each groups with 57 cases; the control group was treated with Simotang oral liquid, while observation group with Bifico on the base of control group; the effects of two groups were compared.

Results：After treatment, the effect of observation group was significantly better than control group(P＜0.05); the score decrease of poor appetite, abdominal distension, nausea and vomiting and loose stool indigestion was greater in the observation group than that of control group(P＜0.05); the level increase of gastrin and motilin in the observation group was better than that of control group; the level decrease of nitrogen monoxidum in the observation group was better than that of control group(P＜0.05).

Conclusion：In treating pediatric functional dyspepsia, combined therapy of Simotang oral liquid and Bifico can increase curative effect and improve symptom and is safe, so it is worthy of clinical promotion.