ISSN 1674-3865  CN 21-1569/R
主管:国家卫生和计划生育委员会
主办:中国医师协会
   辽宁省基础医学研究所
   辽宁中医药大学附属医院

Chinese Pediatrics of Integrated Traditional and Western Medicine ›› 2021, Vol. 13 ›› Issue (4): 353-.

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Clinical study of modified Xiaoqinglong decoction in the treatment of children with bronchial asthma of external-coldness and internal-drink type during acute onset

Objective: To study the clinical effect of modified Xiaoqinglong decoction in the treatment of children with bronchial asthma ofexternal-coldness and internal-drink type.#br# Methods: A total of 80 children with bronchial asthma of external-coldness andinternal-drink type were treated in our hospital between February 2019 and August 2020, and they were divided into observation group and control group, with 40 cases in each group. Both groups were treated with conventional western medicine, and the observation group was also treated given modified Xiaoqinglong decoction, and the use of hormone was reduced by a half. After one week of treatment, the clinical effect wascompared between the two groups, and compare the total traditional Chinese syndrome score, FEV1%, FEV1/FVC, PEF andFeNO before and treatment, the childhood asthma control test and the adverse reactions were evaluated.#br# Results: After treatment, the total effective rates of the observation group and the control groupwere 92.3% and 71.0%, respectively, with statistically significant differences between the twogroups(P<0.05). After one week of treatment, the total score of TCM syndromes in the observation group was significantly lower than that of the control group(P<0.01), lung function was significantly better(P<0.05), FeNO was significantly lower than that of the control group, and the control test of asthmain the observation group was better than that in the control group(P<0.01). No adverse reactions occurred in both groups during the treatment.#br# Conclusion: On the basis of conventional western medicine treatment, the dosage of hormone is halved, and Xiaoqinglong decoction can be used to treat children with  bronchial asthma of external-cold and internal-drink type during acute onset, which is effective and worthy of further clinical promotion.   

  1. Shenzhen Hospital of Beijing University of Chinese Medicine (Longgang), Shenzhen 518100, China
  • Online:2021-08-25 Published:2021-12-13

Abstract: Objective: To study the clinical effect of modified Xiaoqinglong decoction in the treatment of children with bronchial asthma ofexternal-coldness and internal-drink type.
Methods: A total of 80 children with bronchial asthma of external-coldness andinternal-drink type were treated in our hospital between February 2019 and August 2020, and they were divided into observation group and control group, with 40 cases in each group. Both groups were treated with conventional western medicine, and the observation group was also treated given modified Xiaoqinglong decoction, and the use of hormone was reduced by a half. After one week of treatment, the clinical effect wascompared between the two groups, and compare the total traditional Chinese syndrome score, FEV1%, FEV1/FVC, PEF andFeNO before and treatment, the childhood asthma control test and the adverse reactions were evaluated.
Results: After treatment, the total effective rates of the observation group and the control groupwere 92.3% and 71.0%, respectively, with statistically significant differences between the twogroups(P<0.05). After one week of treatment, the total score of TCM syndromes in the observation group was significantly lower than that of the control group(P<0.01), lung function was significantly better(P<0.05), FeNO was significantly lower than that of the control group, and the control test of asthmain the observation group was better than that in the control group(P<0.01). No adverse reactions occurred in both groups during the treatment.
Conclusion: On the basis of conventional western medicine treatment, the dosage of hormone is halved, and Xiaoqinglong decoction can be used to treat children with  bronchial asthma of external-cold and internal-drink type during acute onset, which is effective and worthy of further clinical promotion.

Key words: Bronchial asthma, Acute onset, Xiaoqinglong decoction, External-cold and internal-drink syndrome;Children