Abstract: Objective  To observe the clinical effect of Xiaoer Qingre Huaji powder in the prevention and treatment of febrile convulsion in children.Methods A total of 102 children with febrile convulsion were selected from the pediatric outpatients and inpatients of Zhejiang Hospital of Traditional Chinese Medicine from January 2021 to December 2022,and they were randomly divided into control group (50 cases) and observation group (52 cases).The control group was given conventional treatment,and the observation group was given oral treatment of Xiaoer Qingre Huaji powder on the basis of the the treatment for control group.The two groups were observed continuously for 3 days,and relevant indicators were collected.Three months was set as a follow-up course.During the follow-up,the control group was given diazepam to prevent convulsion,and the observation group was given Xiaoer Qingre Huaji powder to prevent convulsion,and they were followed up for 1 year.The time of fever relief,the number of recurrent convulsions,and the change in TCM syndrome score before and after treatment were counted.The number of convulsions in the two groups during follow-up was counted.Results  The body temperature of the two groups were decreased with treatment time,with the observation group being lower than the control group at 6h,24h,48h and 72h of treatment,and the difference was statistically significant (P<0.05).During the whole process of treatment,the fever was effectively controlled in the observation group,and the the number of reaching peak (body temperature≥39 ℃) was 0.53±0.62,significantly lower than the control group (1.65±2.72);in the 72 hours of treatment,the difference was statistical (P<0.05).At the same time,the TCM syndrome score was significantly lower than that of control group,and the difference was statistically significant (P<0.05).There was no statistical difference in the incidence of adverse reactions (P>0.05) between the two groups.The two groups were followed up for 1 year,the observation group did not have convulsion,while the control group had (0.55±0.55) times of convulsion,the observation group being significantly better than the control group,and the difference was statistically significant (P<0.01).Conclusion Xiaoer Qingre Huaji powder is effective in preventing and treating febrile convulsion in children.It can shorten the fever duration,significantly reduce the frequency of recurrent convulsion,and prevent febrile convulsion recurrence effectively,which is worth clinical promotion and application.

Key words:

Febrile convulsion, Xiaoer Qingre Huaji powder, Treatment, Child